Results 91 to 100 of about 1,190,273 (267)
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Comparison of Patient’s Rights in Developed Countries and Suggestion a Proper Model for Iran
مدیریت اطلاعات سلامت, 2011 Introduction: In health care, emphasis on basic human rights is especially important. Patient’s privacy protection becomes important when the human is exposed to shortcomings of social and health systems. This study was performed to compare the patient’s
Masoumeh Sarbaz, Khalil Kimiafar
doaj
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
ارزیابی عملکرد سیستم اطلاعات داروخانهی بیمارستانهای آموزشی، خصوصی و تأمین اجتماعی شهر اصفهان
مدیریت اطلاعات سلامت, 2013 مقدمه: سیستم اطلاعات داروخانه با پشتیبانی از یک رویکرد درمانی و مدیریت مراقبت دارویی یکی از ارکان ضروری نظام سلامت است، تا اطمینان حاصل شود که دارودرمانی با همان سطح ایمنی و کیفیت مانند دیگر درمانها و خدمات، پشتیبانی و ارزیابی میشود.
Sakineh saghaeiannejad Isfahani +5 more
doaj
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
کاربرد مدارک و اطلاعات پزشکی در تحقیقات از دیدگاه پژوهشگران
مدیریت اطلاعات سلامت, 2008 مقدمه: امروزه تحقیقات در علوم مختلف به عنوان ابزاری قدرتمند و شایان توجه جهت ارزیابی آخرین دستاوردهای علمی به كار میرود. مهمترین ابزار راهگشای محققین در علوم پزشکی برای انجام تحقیقات، مدارك و اطلاعات پزشكی بیماران در بایگانیهای بیمارستانها میباشد ...
Sima Ajami, Faeze Kalbasi, Mahnaz Kabiri
doaj
FEBS Open Bio, EarlyView.A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source