Results 81 to 90 of about 2,648,094 (288)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Designing a Form for Request to Transfusion of Blood and Its Products
One of the methods for knowledge transferring is documentation of procedures done in a documentary process, whether in a paper or electronic format. For creation reporting process of monitoring the rate of blood request, uses, and reactions, also unused ...
Azar Kabirzadeh +4 more
doaj
The Identification of Mistakes in Road Accident Records – Part Two. [PDF]
It has been acknowledged that there are many mistakes in the casualty variables on the police accident report forms. This study shows how a computer based linkage of police and hospital records can be used to routinely identify the mistakes for the ...
Austin, K.P.
core
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
سلامت عمومی و استرس شغلی در كاركنان بخش مدارك پزشکی شاغل در بیمارستانهای استان مازندران
چكیده مقدمه: دستاندركاران حرفههای پزشكی به دلیل بر عهده داشتن مسؤولیت تأمین سلامت و درمان بیماران، تحت تأثیر عوامل متعدد استرسزا هستند. در این پژوهش میزان سلامت عمومی، استرس و عوامل استرسزا در كاركنان بخش مدارك پزشكی بیمارستانهای استان مازندران ...
Azar Kabirzadeh +4 more
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Data Documentation in Patients with Tuberculosis in Razi Hospital of Ghaemshahr, Iran
Introduction: The health information system of hospitals depends on their medical records. Therefore, the detailed documentation, and maintenance of patient records can lead to timely diagnosis and effective treatment of diseases in any country, and ...
Sayede-Shahrebano Rashida +1 more
doaj
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source

