Results 61 to 70 of about 7,859,514 (264)

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Medical Records- a Legal Perspective

Journal of Clinical and Biomedical Sciences, 2018
A medical record is a document containing chronologically written account of a patient’s examina-tion and treatment. A medical record apart from case sheet includes investigatory reports, investigatory samples, referral letter, discharge summary
Abinandana R, Srinivasa Reddy P
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Comparative Study of Mental Health Registry System of United Kingdom, Malaysia and Iran

مدیریت اطلاعات سلامت, 2009
Introduction: In spite of the vast improvement in the area of mental health care delivery in this country, very little attention has been given to the mental health registry.
Hadi Lotfnezhadafshar, Zahra Zareh fazlollahi, Masomeh Khoshkalam, Peyman Rezaihacheso   +3 more
doaj  

Potential application of item-response theory to interpretation of medical codes in electronic patient records [PDF]

, 2011
Background: electronic patient records are generally coded using extensive sets of codes but the significance of the utilisation of individual codes may be unclear. Item response theory (IRT) models are used to characterise the psychometric properties of
Van Staa, Tjeerd; id_orcid, Little, P., Delaney, B., Delaney, Brendan, Wolfe, C., van Staa, Tjeerd, Gulliford Martin C, Grieve Andy, Gulliford, M.C., Charlton, Judith, Gulliford, Martin C., Little, Paul, Martin C Gulliford, Grieve, A., van Staa, T., Yardley, L., Dregan Alex, Dregan, A., Moore, M., Taweel, Adel, Andy Grieve, Moore, Michael, Charlton, J., Dregan, Alex; id_orcid, Taweel, A., Tjeerd van Staa, Dregan, Alex, Yardley, Lucy, van Staa Tjeerd, null null, Wolfe, Charles, Rudd, A., Gulliford, Martin C, Rudd, Anthony, eCRT Research Team, Grieve, Andy, Alex Dregan   +36 more
core   +2 more sources

The Perception of Character Education in Medical School [PDF]

, 2020
The purpose of this study was to examine professors’ and students’ perceptions of curriculum that fosters character in medical school. ‘Character’ can be defined as a desirable personality and the ability to be a good person.
Korean Medical Education Review (의학교육논단)
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Medical Records Committee report 1984

, 1984
When the "Doctor/patient" was essentially a one to one relationship, a Doctor's medical notes were often little more than an "aide memoire" to himself.
Jeffs, David
core  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source