Results 101 to 110 of about 1,146,044 (291)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Rate of Implementation of Standard Codes for Injuries, Burns and Poisonings in Teaching-Hospitals of the Iran, Tehran and Shahid Beheshti Medical Universities

open access: yesمدیریت اطلاعات سلامت, 2009
Introduction: Standard codes and their descriptions are important tools for research, design, implementation and evaluation of the injury control program and its sub-categories.
Faezeh Akhlaghi   +2 more
doaj  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Medical record documentation quality in the hospital accreditation

open access: gold, 2021
Saiedeh Sharifi   +3 more
openalex   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

The association of serum klotho with pulmonary function among US adults: a cross-sectional study

open access: yesBMC Pulmonary Medicine
Background Klotho has been found to be an anti-aging gene, of which the protein expression level declines with age. Lower levels of klotho protein were found to be associated with a variety of chronic diseases including hypertension, chronic kidney ...
Zichong Long, Huaqiao Mu
doaj   +1 more source

Analysis of records by nursing technicians and nurses in medical records

open access: gold, 2020
Larissa de Lima Ferreira   +5 more
openalex   +1 more source

Clustering of patient comorbidities within electronic medical records enables high-precision COVID-19 mortality prediction [PDF]

open access: gold, 2021
Erwann Le Lannou   +5 more
openalex   +1 more source

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