Results 51 to 60 of about 9,867,084 (375)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Constraining Factors of Research from the Viewpoint of Faculty Members of Zahedan University of Medical Sciences

مدیریت اطلاعات سلامت, 2010
Introduction: After human resource training, Research is a basis of cultural, social and economical expansion and university is the main basis of research system.
Afsaneh Karimi, Yosef Mehdipour, Ali Mohammadpour, Samira Pirozanfar   +3 more
doaj  

Effects of HBsAg carriers on pregnancy complications in pregnant women: a retrospective cohort study

Frontiers in Medicine, 2023
ObjectiveHepatitis B virus (HBV) infection is a major health threat worldwide, especially in developing countries. We aimed to investigate the impact of hepatitis B carrier on pregnancy complications in pregnant women, in China.MethodsThis retrospective ...
Mengqing Weng, Jie Wang, Jie Wang, Jingfeng Yin, Wenning Ren, Caiping Wei, Wenshan Yang, Huimin He   +7 more
doaj   +1 more source

Design, implementation, and inferential issues associated with clinical trials that rely on data in electronic medical records: a narrative review [PDF]

, 2023
Alan Leviton, Tobias Loddenkemper
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Disasters and its Effects on Medical Records Department; a Case Report. The Importance of Protection of Patient Information from Flood Damages

مدیریت اطلاعات سلامت, 2010
Introduction: Disasters whether natural or man-made can inflict widespread damage in every society. Disaster effects on hospitals were discussed by many specialties in many fields.
Azar Kabirzadeh, Benyamin Mohsenisaravi, Aghdas Kabirzadeh   +2 more
doaj  

Use of electronic medical records and biomarkers to manage risk and resource efficiencies [PDF]

, 2017
Peer reviewedPublisher ...
Blakey, John, Chisholm, Alison, Kocks, Janwillem W H, Lisspers, Karin, Price, David, Ryan, Dermot, Ställberg, Björn, The Respiratory Effectiveness Group, Thomas, Mike   +8 more
core   +7 more sources

Real-world Evidence versus Randomized Controlled Trial: Clinical Research Based on Electronic Medical Records

Journal of Korean medical science, 2018
Real-world evidence (RWE) and randomized control trial (RCT) data are considered mutually complementary. However, compared with RCT, the outcomes of RWE continue to be assigned lower credibility.
Hun‐Sung Kim, Suehyun Lee, Ju Han Kim
semanticscholar   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

A Comparative Study of the Iran Ministry of Health Patient and Family Education Standards with Joint Commission on Accreditation of Healthcare Organizations

مدیریت اطلاعات سلامت, 2010
Introduction: According to role of patient and family education in the process of patient care, Joint Commission on Accreditation of Healthcare Organizations (JCAHO) has considered the patient and family education standards in the hospital accreditation ...
Ali Mohammadpor, Yosef Mehdipour, Afsaneh Karimi, Ali Rahdari   +3 more
doaj