Results 41 to 50 of about 73,014,182 (263)

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source

Internal consistency, construct validity, and responsiveness of the MRC Prion Disease Rating Scale

Journal of Patient-Reported Outcomes
Background The Medical Research Council-Prion Disease Rating Scale (MRC-PDRS) is a 20-point clinician-reported outcome scale to assess disease progression in patients with prion disease, an invariably fatal neurodegenerative disease caused by misfolded ...
Leah Leidy, Aaron Yarlas, Robert S. Pulido, Jessica Ludwig, Kathleen Glisic, Brian S. Appleby   +5 more
doaj   +1 more source

New directions for the treatment of adrenal insufficiency [PDF]

, 2015
The following funding bodies supported this work: Biotechnology and Biological Sciences Research Council (BBSRC BB/L00267/1, to LG), Rosetrees Trust (to LG), Barts and The London Charity (417/2235, to LG), EU COFUND (PCOFUND-GA-2013-608765, to LG and GRB)
Leonardo Guasti, Hadjidemetriou, I, Guasti, L, Leonardo eGuasti, Gerard Ruiz-Babot, Ruiz-Babot, G, Irene eHadjidemetriou, Irene Hadjidemetriou, Peter James King, Gerard eRuiz-Babot, King, PJ   +10 more
core   +1 more source

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma, Nathan Pavey, Yukiko Tsuji, Amirul Ab Ghapar, Mehdi A.J. van den Bos, Bronwen Orden, Grace Lee, Linda Mekhael, Julie Ryder, Cláudia Santos Silva, David McDonald, Fakhria Kakar, Con Yiannikas, Matthew C. Kiernan, David A. Brown, Parvathi Menon, Steve Vucic   +16 more
wiley   +1 more source

Multipoint incremental motor unit number estimation versus amyotrophic lateral sclerosis functional rating scale and the medical research council sum score as an outcome measure in amyotrophic lateral sclerosis

Annals of Indian Academy of Neurology, 2014
Introduction: Monitoring the disease progression in amyotrophic lateral sclerosis (ALS) is a challenge due to different rates of progression between patients.
Sujit Abajirao Jagtap, Abraham Kuruvilla, Preetha Govind, Muralidharan D Nair, C Sarada, Ravi Prasad Varma   +5 more
doaj   +1 more source

Vascular Disease, Non‐Steroidal Anti‐Inflammatory Drugs and Risk of Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives A history of vascular disease has been shown to be associated with an increased risk of Parkinson's disease, but this may be due to reverse causation. In addition, non‐steroidal anti‐inflammatory drugs are thought to reduce Parkinson's disease risk, but evidence is inconsistent and confounding by prior vascular disease is possible ...
Clare Wotton, Carol Hermon, Sarah Floud, Gillian Reeves, Isobel Barnes   +4 more
wiley   +1 more source

Medical Council annual report 1980 [PDF]

, 2000
The first year of the Medical Council cannot be measured on any time scale. It could date from the passing of the Act in 1978, or from the first meeting in April 1979, but it really began with the Registrar's taking up his appointment in September ...
Medical Council
core  

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

Evaluation of maximum inspiratory and expiratory pressure in patients with chronic obstructive pulmonary disease

Egyptian Journal of Chest Disease and Tuberculosis, 2014
Respiratory muscle dysfunction is a cardinal feature of acute and chronic respiratory failure in COPD. Diaphragm and accessory inspiratory muscles face increased load due to increased lung resistance and elastance, as well as increased ventilatory demand.
M. Khalil, K. Wagih, O. Mahmoud
doaj   +1 more source

Effect of Early Mobilization on Respiratory and Limb Muscle Strength and Functionality of Nonintubated Patients in Critical Care: A Feasibility Trial

Critical Care Research and Practice, 2020
Purpose. To assess the potential effectiveness or efficacy of early mobilization on respiratory and peripheral muscle strengths and functionality in nonintubated patients. Methods.
Maria Karoline Richtrmoc, Wagner Souza Leite, Anielle Martins Azevedo, Raissa Farias Correia, Rômulo de Aquino Coelho Lins, Wildberg Alencar Lima, Caio César Araújo Morais, Rodrigo Rios Pereira, Monique Bandeira, Carlos Eduardo Santos Rego Barros, Amina Maria Soares de Lima, Maria Glória Rodrigues-Machado, Daniella Cunha Brandão, Armèle Dornelas De Andrade, Maria Inês Remigio de Aguiar, Shirley Lima Campos   +15 more
doaj   +1 more source