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Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson+11 more
wiley +1 more source
Mentoring program design and implementation in new medical schools [PDF]
Purpose: Mentoring is considered a valuable component of undergraduate medical education with a variety of programs at established medical schools. This study presents how new medical schools have set up mentoring programs as they have developed their ...
Alice Fornari+8 more
core +2 more sources
Medical Spanish in US Medical Schools: a National Survey to Examine Existing Programs
P. Ortega+6 more
semanticscholar +1 more source
Managing medication in schools [PDF]
Increasing numbers of children and young people are prescribed medication to be taken in school. This article discusses general principles of prescribing medication for use in school, specific conditions for which medicines may be prescribed, and the key role of nurses in liaison with schools.
openaire +4 more sources
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu+11 more
wiley +1 more source
Factors Affecting Learning of Anatomy: Students\' Viewpoints [PDF]
Introduction: Anatomy is of outmost importance for medical students because of its application in medical practice. Students are a main source of information for quality and effectiveness of education and their views can be used to improve teaching and ...
Semira Mehralizadeh+4 more
doaj
Dr. Mary Edwards Walker: years ahead of her time. [PDF]
Women phsycians in the United States were virtually nonexistent in the early to mid-1800s. Traditional medical schools still did not accept women, and few secretarian or eclectic medical schools were beginning to open their doors to female students.
Bogar, MD, Linda J.+5 more
core +1 more source
The Physio-Medical School? [PDF]
North East, Pa., March 15, 1897. To the Editor: —Can you give through the columns of your valuableJournala short history of what is known hereabouts as the physio-medical school of the practice of medicine. I would like to know something as to its origin, wherein it differs from the Regular, how many colleges it has, and as to what States recognize ...
openaire +2 more sources
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Cisplatin is used in the treatment of ovarian and testicular cancer. Twenty percent of patients cannot be optimally treated because of sensory neurotoxicity.
Stephanie J. Fischer+3 more
doaj