Results 241 to 250 of about 5,849,921 (287)

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Post-Pandemic Virtual Teaching Self-Efficacy: Insights from Medical Educators at Shiraz University of Medical Sciences, Iran. [PDF]

Middle East J Dig Dis
Rezvani AR, Zarifsanaiey N, Shahmirzalou P, Mehrabi M, Rahmati L, Safarpour AR.   +5 more
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Explaining the classroom behavior process of medical sciences students: A grounded theory. [PDF]

J Educ Health Promot
Moradi Y, Fereidouni Z, Abdollahi A, Jeihooni AK, Poornasiri N, Jokar Z, Dehghani S, Karimi S, Keshavarzi MH.   +8 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Assessment of Burnout and its Related Factors in the Faculty Members and Medical Staff of Neyshabur University of Medical Sciences, Iran, in 2022. [PDF]

Iran J Nurs Midwifery Res
Ebrahimpour-Sadagheyani H, Tatari F.
europepmc   +1 more source

Management competencies at different organizational levels: A study of Tabriz University of Medical Sciences. [PDF]

J Educ Health Promot
Yoshari P, Naghshi M, Musavi S, Khodayari-Zarnaq R.   +3 more
europepmc   +1 more source

"Establishing pathways to excellence in the teaching profession": an exploration of teachers' experiences on sustaining motivation in Medical sciences universities. [PDF]

BMC Med Educ
Bahramnezhad F, Keshmiri F.
europepmc   +1 more source

Assessment of HIV Infection in HIV Patients Admitted to Pakistan Institute of Medical Sciences, Islamabad, Pakistan. [PDF]

AIDS Res Treat
Zubair A, Ali M, Munir R, Hossain MB.
europepmc   +1 more source

Challenges and Solutions in Medical Tourism at Iran University of Medical Sciences: A Qualitative Study. [PDF]

Med J Islam Repub Iran
Hosseinabadi N, Badizadeh A, Zaboli R, Nemati A.   +3 more
europepmc   +1 more source