Results 141 to 150 of about 3,643,790 (352)
Targeted dephosphorylation of TFEB promotes its nuclear translocation
Summary: Reversible phosphorylation of the transcription factor EB (TFEB) coordinates cellular responses to metabolic and other stresses. During nutrient replete and stressor-free conditions, phosphorylated TFEB is primarily localized to the cytoplasm ...
Jin-Feng Zhao +8 more
doaj +1 more source
We examined the current situation of studies on health in Germany, especially medical anthropology by v. Weizsacker and v. Gebsattel, medical sociology, social medicine and general medicine in the faculties of medicine of German universities and the new ...
石井, 誠士
core
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Summary: The presence of calcified nodule (CN) is a significant characteristic of atherothrombosis in acute coronary syndrome (ACS). However, its characteristics continue to be understudied. This review aimed to further investigate these characteristics.
Roy Bagus Kurniawan +8 more
doaj +1 more source
PROGRESS MEDICAL SCIENCE MEDICINE [PDF]
openaire +1 more source
Gerald A. Isenberg, MD, FACS [PDF]
As Professor of Surgery, Division of Colorectal Surgery; Director, Surgical Undergraduate Education, Jefferson Medical College (JMC); Program Director, Colorectal Residency Program, Thomas Jefferson University Hospital; and Chair, Curriculum Committee ...
core +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source

