Results 41 to 50 of about 530,413 (266)

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski, Rebecca Ronsley, Shannon M. Stasi, Jeffrey Stevens, Erin R. Rudzinski, Christina M. Lockwood, Sarah E. S. Leary, Bonnie L. Cole, Michelle A. Ting, Vera Paulson   +9 more
wiley   +1 more source

Simulation study of a low-cost Slide-Through PET scanner based on narrow flat panels with monolithic detectors

Frontiers in Physics
BackgroundPatient throughput in conventional PET systems is constrained by limited system sensitivity and the need for bed positioning. This study proposes a cost-effective Slide-Through PET (ST-PET) design based on two narrow monolithic LYSO detector ...
Elke Dhaenens, Boris Vervenne, Maya Abi Akl, Jens Maebe, Christian Vanhove, Stefaan Vandenberghe   +5 more
doaj   +1 more source

Optimal Deep Learning Architecture for Automated Segmentation of Cysts in OCT Images Using X-Let Transforms

Diagnostics, 2023
The retina is a thin, light-sensitive membrane with a multilayered structure found in the back of the eyeball. There are many types of retinal disorders.
Reza Darooei, Milad Nazari, Rahele Kafieh, Hossein Rabbani   +3 more
doaj   +1 more source

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

Performance evaluation of a medium axial field-of-view sparse PET system based on flat panels of monolithic LYSO detectors: a simulation study

EJNMMI Physics
Background The combination of longer axial field-of-view (AFOV) and time-of-flight positron emission tomography (PET) has significantly improved system sensitivity and, as a result, image quality.
Maya Abi-Akl, Jens Maebe, Boris Vervenne, Othmane Bouhali, Christian Vanhove, Stefaan Vandenberghe   +5 more
doaj   +1 more source

Classification of morphologic changes in photoplethysmographic waveforms

Current Directions in Biomedical Engineering, 2016
An ever increasing number of research is examining the question to what extent physiological information beyond the blood oxygen saturation could be drawn from the photoplethysmogram.
Tigges Timo, Music Zenit, Pielmus Alexandru, Klum Michael, Feldheiser Aarne, Hunsicker Oliver, Orglmeister Reinhold   +6 more
doaj   +1 more source

Pannexin 1 Is Critically Involved in Feedback from Horizontal Cells to Cones

Frontiers in Molecular Neuroscience, 2017
Retinal horizontal cells (HCs) feed back negatively to cone photoreceptors and in that way generate the center/surround organization of bipolar cell receptive fields. The mechanism by which HCs inhibit photoreceptors is a matter of debate.
Valentina Cenedese, Wim de Graaff, Tamás Csikós, Mitali Poovayya, Georg Zoidl, Maarten Kamermans, Maarten Kamermans   +6 more
doaj   +1 more source

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Quantitative analysis of patient motion in walk-through PET scanner and standard axial field of view pet scanner using infrared-based tracking

EJNMMI Physics
Background Long-axial field-of-view (LAFOV) Positron Emission Tomography (PET) scanners provide high sensitivity, but throughput is limited because of time-consuming patient positioning.
Rabia Aziz, Jens Maebe, Florence Marie Muller, Yves D’Asseler, Stefaan Vandenberghe   +4 more
doaj   +1 more source

Pediatric Oncology Nursing Competencies in Latin America and the Caribbean: A Scoping Review to Inform Practice, Education, and Research

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Nurses are central to cancer care for children and adolescents, yet no comprehensive synthesis has defined essential core competencies for pediatric oncology nursing (PON) practice internationally, particularly in Latin America and the Caribbean (LAC).
Luís Carlos Lopes‐Júnior, Edmara Bazoni Soares Maia, Soad Fuentes‐Alabí, Courtney E. Sullivan, Monnie Abraham, Mauricio Maza, Liliana Vásquez Ponce, Regina Aparecida Garcia Lima   +7 more
wiley   +1 more source