Results 91 to 100 of about 614,996 (241)

Effect of Acupressure on Low Back Pain and Fatigue after Coronary Artery Angioplasty through Femoral Artery: A Randomized Controlled Clinical Trial

Journal of Mazandaran University of Medical Sciences, 2022
Background and purpose: Complaints of low back pain and fatigue caused by prolonged lying on the back are complications of angioplasty. The aim of this study was to evaluate the effect of acupressure on severity of low back pain and fatigue in patients ...
Fatemeh Rezvani, Vida Shafipour, Masoumeh Bagheri Nesami, Nadali Esmaeili Ahangarkolai, Ali Asghar Farsavian, Seyed Nouraddin Mousavinasab   +5 more
doaj  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Swiss recommendations for the management of varicella zoster virus infections. [PDF]

, 2007
Infections with varicella zoster virus (VZV) are common viral infections associated with significant morbidity. Diagnosis and management are complex, particularly in immunocompromised patients and during pregnancy.
Aebi, C., Agosti, R., Büchner, S., Coradi, B., Garweg, J., Gerber, S., Hirsch, H., Kempf, W., Kind, C., Lauper, U., Lautenschlager, S., Meylan, P., Nadal, D., Reusser, P., Ruef, C., Wunderli, W.   +15 more
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Trends of Representation of Women in Professional Medical Societal Leadership in the United States and Europe

JACC: Advances
Background: There continue to be significant gender disparities with women being underrepresented in medical professional society leadership roles, despite more women entering medical school.
Sherna B. Menezes, MBBS, Ashleigh N. Shenton, MD, Allison G. Hays, MD, Cynthia C. Taub, MD, MBA   +3 more
doaj   +1 more source

Medical advice-seeking behaviors based on transaction cost theory

Cost Effectiveness and Resource Allocation, 2018
Background Given the global trend of aging societies, medical expenditure has hit record highs in many countries. Because medical advice-seeking behaviors can affect the health of whole societies, how members of a society make medical-related decisions ...
Shih Han Lin, Tom M. Y. Lin
doaj   +1 more source

Evaluation of recovery after intravenous sedation [PDF]

, 2017
The Intravenous Sedation (IVS) Guideline Working Group of the Japanese Dental Society of Anesthesiology (JDSA) formulated guidelines for intravenous conscious sedation in dentistry.
Fujisawa, Toshiaki, Shibuya, Makiko
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

The Politics of Vodou: Aids, Access to Health Care and the Use of Culture in Haiti [PDF]

, 2007
During the past few years, the AIDS campaign in Haiti has been targeting Vodou officiants and organizations. These awareness and training programmes in- form officiants about the transmission and prevention of AIDS, tests for HIV and anti- retroviral ...
Benoît, Catherine
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source