Results 81 to 90 of about 614,996 (241)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

X Jornada Científica Provincial de los Servicios Médicos del Ministerio del Interior en Santiago de Cuba

open access: yesMedisan
En Santiago de Cuba, los días 25 y 26 de mayo de este año, se realizó la X Jornada Científica Provincial de los Servicios Médicos del Ministerio del Interior, bajo el auspicio del Capítulo Provincial de la Sociedad de Medicina General Integral y con el ...
Yuri Alvarez Magdariaga   +1 more
doaj  

Medical societies and patient-centered communication: A review of current practices and future directions

open access: yesContinence Reports
Introduction: Patient-centered communication (PCC) is a vital component of high-quality medical care, fostering respectful, responsive interactions that align clinical decisions with patient values.
Filippos Nikitakis   +10 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

50 Years of the Journal of the Brazilian College of Surgeons: History, Evolution and Future Prospects [PDF]

open access: yesRevista do Colégio Brasileiro de Cirurgiões
This article celebrates the 50th anniversary of the continuous publication of the Journal of the Brazilian College of Surgeons (RCBC), revisiting its trajectory from the beginning to the present day.
GERSON ALVES PEREIRA JUNIOR   +3 more
doaj   +1 more source

Just shamans and healers or indigenous medical systems? A critical discourse analysis of the categories of shamans and healers as constructed by social science texts [PDF]

open access: yes
"Just as even a single sentence has traditionally been taken to imply a whole language so a single discourse implies a whole society." Language and Power, N. Fairclough.
Moreno-Leguizamon, Carlos
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

A Faculty Development Workshop for High-Value Care Education Across Clinical Settings. [PDF]

open access: yes, 2018
IntroductionDespite rising health care costs, trainees frequently do not receive formal high-value care (HVC) training. As medical education often occurs through informal learning, it is imperative that medical educators be prepared to teach HVC concepts
Avery, Carolyn   +7 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Toward Interdisciplinary Collaboration between Electrochemistry and Physiology: Status Quo, Challenges, and Prospects

open access: yesElectrochemistry
Interdisciplinary collaboration among various fields is essential for advancements in science. In medicine, innovative approaches created through the collaboration are required for the analysis of mechanisms underlying complicated biological events as ...
Hiroshi HIBINO
doaj   +1 more source

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