Results 51 to 60 of about 7,572,903 (382)

ТЕРАПЕВТИЧЕСКИЕ ОБЩЕСТВА СЕВЕРО–КАВКАЗСКОГО ФЕДЕРАЛЬНОГО ОКРУГА

Архивъ внутренней медицины, 2012
In the North Caucasus Federal District operate seven scientific medical societies of physicians as an autonomous. Societies have a different history and experience.
А. В. Ягода
doaj   +1 more source

Hope in the era of precision oncology: a qualitative study of informal caregivers’ experiences

BMJ Open, 2023
Objectives To explore informal caregivers’ perspectives on precision medicine in cancer care.Design Semi-structured interviews with the informal caregivers of people living with cancer and receiving targeted/immunotherapies.
Alex Broom, Zarnie Lwin, Mustafa Khasraw, Barbara Prainsack, Katherine Kenny, Leah Williams Veazey, Michelle Peterie, Alexander Page, Claire E. Wakefield, Malinda Itchins   +9 more
doaj   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

International experiences in the development and implementation of guideline-based quality indicators: a qualitative study

BMJ Open, 2021
Objectives Evidence-based clinical guidelines play an important role in healthcare and can be a valuable source for quality indicators (QIs). However, the link between guidelines and QI is often neglected and methodological standards for the development ...
Jochen Schmitt, Monika Nothacker, Marie Bolster, Mirco Steudtner, Katrin Arnold, Stefanie Deckert, Monika Becker, Ina Kopp   +7 more
doaj   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

The flight of the white collars [PDF]

, 2013
By analyzing two novel data sets from Turkey, we provide empirical evidence for yet another negative consequence of civil conflicts. We show that the long running civil cinflict in Turkey has been driving away doctors and other medical personnel from ...
Kıbrıs, Arzu, Kibris, Arzu
core  

The introduction of sickness insurance in Spain in the first decades of the Franco dictatorship (1939-1962) [PDF]

, 2013
[Abstract:]Using new statistical data on financing, coverage and economic and health care provisions, this article analyses how sickness insurance was introduced, managed and extended in Spain, under the Franco dictatorship, between 1939 and 1962. This
Pons Pons, Jerònia, Vilar Rodríguez, Margarita   +1 more
core   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Amphibian Contributions to Ecosystem Services [PDF]

, 2014
Ecosystems provide essential services for human society, which include provisioning, regulating, cultural, and supporting services. Amphibians provide provisioning services by serving as a food source for some human societies ...
Babbitt, Kimberly J., Hocking, Daniel J.
core   +1 more source

New directions in building a scientific social network: Experiences in the Supercourse project and application to Central Asia. [PDF]

, 2012
Introduction: Networking leaders in the field of public health and medicine is very important for improving health locally and globally, especially in times of disaster.
Hennon, Meredith, LaPorte, Ronald E, Linkov, Faina, Shubnikov, Eugene   +3 more
core   +3 more sources