Results 71 to 80 of about 38,633 (297)
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Off-label prescriptions in diabetic foot
Jornal Vascular Brasileiro, 2014 Prescription of a drug outside of the indications for which it was originally approved by regulators is internationally known as "off-label" prescription.
Luís Jesuíno de Oliveira Andrade +3 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
The words of prevention, part I: changing the model
Revista Brasileira de Medicina de Família e Comunidade, 2015 Objective: this part I article explores the different meanings of relevant keywords for General Practice/Family Medicine (GP/FM) in the prevention domain.
Marc Jamoulle +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
PubMed: Using Subject Headings
, 2020 This interactive tutorial helps students learn about using PubMed\u27s medical subject headings (MeSH) in a search strategy. Students will learn what a subject heading is and how it works in a search. Following the prompts, students will look up terms in
Williams, Betsy
core
Authority control. Teorie, applicazioni e prospettive di sviluppo [PDF]
, 2004 The authority control, though being a process which integrates the catalogue architecture – and which assures the indexes quality (author, title, descriptor) and supports the relational and syndetic structure of the catalogue, endorsing capabilities of ...
Bozzarelli, Oriana
core
Medical subject heading (MeSH) terms used in each database.
, 2022 (DOCX)
Dina Garniasih (12867486) +3 more
core +1 more source
Unification of Subject Description of Aggregated Records in National Repository of Grey Literature [PDF]
, 2016 The diploma thesis focuses on subject description unification methods in records aggregated from different sources in digital repositories, using the example of the National Repository of Grey Literature (NRGL).
Charvátová, Michaela
core +1 more source