Results 81 to 90 of about 562 (218)
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
KRAS and BRAF Mutations as Prognosis Factors in Breast Cancer
Health Research in AfricaIntroduction. Breast cancer is most often linked to genetic factors. The main signaling pathways encountered in this pathology are PIK3/AKT/mTOR and RAS/RAF/MEK/ERK. The latter is much less activated in breast cancer.
Ngo Pambe CJ +3 more
doaj +1 more source
MEDICAL SUBJECT HEADINGS IN MEDLARS.
Bulletin of the Medical Library Association, 1996 Use of an identical subject heading list for both machine searching and publication creates problems. Necessary compromises include precoordination of some headings for publication and use of some coordinates in the computer system that are not appropriate for a printed index.
openaire +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Prehospital use of point-of-care tests by community health workers: a scoping review
Frontiers in Public HealthIntroductionPoint-of-Care Tests (POCTs) are utilized daily in resource abundant regions, however, are limited in the global south, particularly in the prehospital setting.
Daniel Ebbs +4 more
doaj +1 more source
Association between food intake and oral health in elderly: SEPAHAN systematic review no. 8
Dental Research Journal, 2011 Dental status may influence food intake. The aim of this review was to summarize the earlier investigations on the association between food intake and dental status.
Shantia Kazemi +6 more
doaj +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Ciencia y Enfermería, 2012 A pesquisa objetivou caracterizar os trabalhos produzidos e sintetizar a contribuição destes para o enfoque das ações educativas desenvolvidas por enfermeiros brasileiros com adolescentes em situação de vulnerabilidade às DST/Aids por meio da revisão ...
Izaildo Tavares Luna +5 more
doaj
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source