Results 151 to 160 of about 16,376,813 (311)

Making medical records more resilient [PDF]

, 2007
Thesis (S.M.)--Massachusetts Institute of Technology, Engineering Systems Division, Technology and Policy Program, 2007.This electronic version was submitted by the student author.
Rudin, Robert (Robert Samuel)
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Analysis of early diagnosis methods for asymmetric dementia in brain MR images based on genetic medical technology. [PDF]

Open Life Sci, 2023
Zhang X, Tang N, Yin Y, Zhou J, Jiang R, Sheng J, Zhu J.   +6 more
europepmc   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

An After-Hours Virtual Care Service for Children With Medical Complexity and New Medical Technology: Mixed Methods Feasibility Study. [PDF]

JMIR Pediatr Parent, 2023
Babayan K, Keilty K, Esufali J, Grajales Iii FJ, Connected Care Live for Family Caregivers Advisory Group.   +4 more
europepmc   +1 more source

Medical Center, 1951 status

, 1951
This glass lantern slide features an aerial view of the Medical Center campus of the Medical College of South Carolina in ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
core  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Retracted: Diagnosis of Chronic Kidney Disease by Three-Dimensional Contrast-Enhanced Ultrasound Combined with Augmented Reality Medical Technology. [PDF]

J Healthc Eng, 2023
Healthcare Engineering JO.
europepmc   +1 more source

Editorial: High-tech personalized healthcare in movement disorders

Frontiers in Neurology
Alessandro Zampogna, Alessandro Zampogna, Luigi Borzì, Carolina Soares, Carolina Soares, Florenc Demrozi   +5 more
doaj   +1 more source

Medical College building, 1914

, 1914
This glass lantern slide features a ground view of the Medical College Building of the Medical College of the State of South Carolina in ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
core