Results 51 to 60 of about 1,943,319 (338)

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

FEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga, Kazuki Harada, Takuya Yamauchi, Tetsuya Kitaguchi, Masami Yokota Hirai, Mitsuharu Matsumoto, Takashi Tsuboi   +6 more
wiley   +1 more source

A blockchain-based secure storage scheme for medical information [PDF]

arXiv, 2022
Medical data involves a large amount of personal information and is highly privacy sensitive. In the age of big data, the increasing informatization of healthcare makes it vital that medical information is stored securely and accurately. However, current medical information is subject to the risk of privacy leakage and difficult to share.
arxiv  

Accelerators for Medical Applications - Radio Frequency Powering [PDF]

CERN Yellow Report CERN-2017-004-SP pp. 119-150, 2018
This paper reviews the main types of radio-frequency powering systems which may be used for medical applications. It gives the essentials on vacuum tubes, including tetrodes, klystrons, and inductive output tubes, and the essentials on transistors. The basics of combining systems, splitting systems, and transmission lines are discussed.
arxiv   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

FEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze, Stéphane Canaan, Alexandre Gouzy, Pierre Santucci   +3 more
wiley   +1 more source

СОМАТОМЕТРИЧЕСКАЯ ДИАГНОСТИКА АНДРОГЕННОЙ НЕДОСТАТОЧНОСТИ И ЕВНУХОИДИЗМА

Sovremennye Issledovaniâ Socialʹnyh Problem, 2015
Для выявления андрогенной недостаточности и евнухоидизма, как проявлений гипогонадизма, у мужчин в постпубертатном периоде наиболее простым и доступным методом является антропометрия, Среди основных антропометрических методик были неоднозначные ...
Anatoly Stepanovich Pulikov, Olga Leonidovna Moskalenko, Nikolai Petrovich Kuzenkov, Olga Isaevna Zaitseva   +3 more
doaj   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

FEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma, Jennifer R. Deuis, Xinying Jia, Theo Crawford, Sassan Rahnama, Eivind A. B. Undheim, Irina Vetter, Yanni K. ‐Y. Chin, Mehdi Mobli   +8 more
wiley   +1 more source

Clinicians’ Perceptions of Picture Archiving and Communication System (PACS) Use in Patient Care in Eastern Province Hospitals in Saudi Arabia

Journal of Multidisciplinary Healthcare, 2021
Nouf Al-Kahtani, Esra Al-Dhaif, Noor Alsaihtati, Khalid Farid, Suzan AlKhater Department of Health Information Management and Technology, College of Public Health, Imam Abdulrahman Bin Faisal University, Dammam, Saudi ArabiaCorrespondence: Nouf Al ...
Al-Kahtani N, Al-Dhaif E, Alsaihtati N, Farid K, AlKhater S   +4 more
doaj  

The power of microRNA regulation—insights into immunity and metabolism

FEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto, Nicola Manfrini, Stefano Biffo   +2 more
wiley   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

Rapid Review of Generative AI in Smart Medical Applications [PDF]

With the continuous advancement of technology, artificial intelligence has significantly impacted various fields, particularly healthcare. Generative models, a key AI technology, have revolutionized medical image generation, data analysis, and diagnosis. This article explores their application in intelligent medical devices.
arxiv   +1 more source