Results 61 to 70 of about 16,376,813 (311)
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
, 1989 Thesis (M.S.)--Harvard University--Massachusetts Institute of Technology Division of Health Sciences and Technology, Program in Medical Engineering and Medical Physics, 1989.Includes bibliographical references (leaves [165]-[172]).by Henry C.
Chueh, Henry C
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NMR studies of intracellular sodium in the perfused frog heart [PDF]
, 1986 Thesis (Ph. D.)--Massachusetts Institute of Technology, Harvard-MIT Division of Health Sciences and Technology Program in Medical Engineering and Medical Physics, 1986.MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIENCE.Bibliography: leaves 140-153.by ...
Burstein, Deborah
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Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The membrane, interstitium, lymphatic system : a model of lung water dynamics [PDF]
, 1984 Thesis (Ph.D.)--Harvard--Massachusetts Institute of Technology Division of Health Sciences and Technology Program in Medical Engineering and Medical Physics, 1984.MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIENCE.Bibliography: leaves 193-202.by David ...
Sebok, David Albert
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The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
The 'economics' of medical technology.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1993 The word 'economics' is used in this paper in its widest sense, referring to issues that 'influence the management, regulation and government of an enterprise'. In addition to the obvious monetary issues in health-care technology, social, ethical, legal and cultural issues are also discussed.
Járos, G.G., Boonzaier, D.A.
openaire +2 more sources
Regulation of drug delivery from porous polymer matrices using oscillating magnetic fields
, 1984 Thesis (Ph.D.)--Massachusetts Institute of Technology, Dept. of Medical Engineering and Medical Physics, 1984.MICROFICHE COPY AVAILABLE IN ARCHIVES AND SCIENCE.Includes bibliographical references.by Elazer Reuven Edelman.Ph ...
Edelman, Elazer R
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Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source