Results 51 to 60 of about 16,376,813 (311)

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Breaking down barriers: promoting journals beyond the page with open access journal clubs

open access: yesBJPsych Bulletin
In 2020, during the early days of the COVID-19 pandemic, the British Journal of Psychiatry (BJPsych) established a series of free online teaching sessions called BJPsych Journal Clubs.
Angharad N. de Cates   +4 more
doaj   +1 more source

A comprehensive study of a similarity criterion in cardiac computerized tomography images enhancement

open access: yesRevista Facultad de Ingeniería Universidad de Antioquia, 2020
This research focuses on the study of a particular filter based on a similarity criterion that has been applied to improve the information contained in images acquired using different cardiac imaging modalities. The primary attention of this study is to
Antonio José Bravo Valero   +3 more
doaj   +1 more source

Overcoming Pilotitis in Digital Medicine at the Intersection of Data, Clinical Evidence, and Adoption

open access: yesAdvanced Intelligent Systems, 2022
Worldwide, digital medicine technologies are being developed at a rapid rate. While these digital medicine technologies offer the potential to transform and revolutionize health care, many are at risk of stalling and remaining in the pilot stage, known ...
Mathias Egermark   +4 more
doaj   +1 more source

Assessment of the effectiveness of medical simulators in the practical training of medical students: Preliminary results in MU-Varna [PDF]

open access: yes, 2019
INTRODUCTION: Nowadays, simulators have become part of most medical universities’ educational strategy. In recent years, Medical University of Varna has been equipped with the most modern medical simulators, aiming to meet the practical training needs of
Chernogorova, Yanita; Medical University of Varna   +2 more
core   +7 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

CORRESPONDENCE MATCHING IN 3D MODELS FOR 3D HAND FITTING

open access: yesInformatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska
Upper limb prosthetic is an area of medical research and development that aims to restore functionality and improve the quality of life of people affected by the loss of one or both upper limbs.
Maksym Tymkovych   +5 more
doaj   +1 more source

Izazovi produljenja ljudskoga života na razmeđu poboljšanja i agonije

open access: yesDiacovensia, 2020
The main aim of this paper is to present two different forms of human life extension. On the one hand there is dysthanasia, i.e. therapeutic persistence in the provision of life-sustaining measures to terminally ill patients, and on the other hand ...
Odilon-Gbènoukpo Singbo   +2 more
doaj   +1 more source

Medical Science & Technology

open access: yes, 2014
RWTH-Themen : Berichte aus d. Rheinisch-Westfälischen Technischen Hochschule Aachen 2014(1), (2014).
Hamacher, Angelika, Busse, Sabine
openaire   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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