Results 71 to 80 of about 2,307,247 (311)
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
CORRESPONDENCE MATCHING IN 3D MODELS FOR 3D HAND FITTING
Upper limb prosthetic is an area of medical research and development that aims to restore functionality and improve the quality of life of people affected by the loss of one or both upper limbs.
Maksym Tymkovych +5 more
doaj +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Constructivism and Training at the Medical College
In the modern democratization and humanization of college education, the implementation of personality-oriented learning is associated with the introduction of innovations in the educational process.
Filkova, Silviya; TS Rehabilitator, Medical College, Medical University of Varna +1 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Advanced sensors/electrodes and signal processing techniques provide powerful tools to analyze surface electromyographic signals (sEMG) and their features, to decompose sEMG into the constituent motor unit action potential trains, and to identify ...
Merletti Roberto +5 more
doaj +1 more source
The transformation of semi higher medical education into university-college education is a step towards its harmonisation with the European educational framework.
Atanasova, Ani; Dental Technology, Medical College – Varna, Medical University – Varna +3 more
core +1 more source
Artificial Intelligence: Will It Replace Human Medical Doctors?
Development of artificial intelligence is expected to revolutionize today’s medicine. In fact, medicine was one of the areas to which advances in artificial intelligence technology were first applied.
연세대학교 의과대학
core +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

