Results 91 to 100 of about 15,500,666 (311)
Journal of Inflammation ResearchYufeng Zhou,1,2,* Hongzhen Du,1,* Qian Zhang,1,2 Fantao Meng,2,3 Yimeng Wang,1,2 Jilin Fan,2 Wei Li21School of Special Education and Rehabilitation, Shandong Medical and Pharmaceutical University, Yantai, 264003, People’s Republic of ...
Zhou Y +6 more
doaj
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Medical College building, 1914
, 1914 This glass lantern slide features a ground view of the Medical College Building of the Medical College of the State of South Carolina in ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
, 1951 This glass lantern slide features an aerial view of the Medical Center campus of the Medical College of South Carolina in ...
Medical College of South Carolina (1952-1969). Department of Medical Illustration
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A Review of the State of the Art for the Internet of Medical Things
SciThe technological developments in the Internet of Things (IoT), data science, artificial intelligence, wearable sensors, remote monitoring, decision support systems, fog, and edge systems have transformed digital healthcare. Especially after the pandemic,
Peter Matthew +8 more
doaj +1 more source
Identifying and Quantifying Neurological Disability via Smartphone
Frontiers in Neurology, 2018 Embedded sensors of the smartphones offer opportunities for granular, patient-autonomous measurements of neurological dysfunctions for disease identification, management, and for drug development.
Alexandra K. Boukhvalova +8 more
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Integrating digital and narrative medicine in modern healthcare: a systematic review
Medical Education OnlineThe increasing integration of digital technologies in healthcare, such as electronic health records, telemedicine, and diagnostic algorithms, improved efficiency but raised concerns about the depersonalization of care. Narrative medicine has emerged as a
Efthymia Efthymiou
doaj +1 more source