Results 81 to 90 of about 4,286,167 (302)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Identifying and Quantifying Neurological Disability via Smartphone

open access: yesFrontiers in Neurology, 2018
Embedded sensors of the smartphones offer opportunities for granular, patient-autonomous measurements of neurological dysfunctions for disease identification, management, and for drug development.
Alexandra K. Boukhvalova   +8 more
doaj   +1 more source

Barriers to the adoption of health information technology [PDF]

open access: yes, 2011
Information Technology (IT) is successfully applied in a diverse range of fields. Though, the field of Medical Informatics is more than three decades old, it shows a very slow progress compared to many other fields in which the application of IT is ...
Nugawela, Saliya, Sahama, Tony
core   +1 more source

Ambulance service operational improvement [PDF]

open access: yes, 2013
This document is the accepted manuscript version of a Published Work that appeared in final form in International Paramedic Practice copyright © MA Healthcare, after peer review and technical editing by the Publisher.
Alinier, Guillaume, Hutton, David
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

A Review of the State of the Art for the Internet of Medical Things

open access: yesSci
The technological developments in the Internet of Things (IoT), data science, artificial intelligence, wearable sensors, remote monitoring, decision support systems, fog, and edge systems have transformed digital healthcare. Especially after the pandemic,
Peter Matthew   +8 more
doaj   +1 more source

The Workforce Needs of New Jersey's Pharmaceutical and Medical Technology Industry [PDF]

open access: yes, 2007
This report is based on an online survey conducted in spring 2006 of pharmaceutical and medical technology companies in New Jersey. It identifies the current and future workforce needs of the pharmaceutical and medical technology industry in New ...

core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Integrating digital and narrative medicine in modern healthcare: a systematic review

open access: yesMedical Education Online
The increasing integration of digital technologies in healthcare, such as electronic health records, telemedicine, and diagnostic algorithms, improved efficiency but raised concerns about the depersonalization of care. Narrative medicine has emerged as a
Efthymia Efthymiou
doaj   +1 more source

Innovative Medical Technology and the Treatment Decision-Making Process in Multiple Sclerosis: A Focus Group Study to Examine Patient Perspectives

open access: yesPatient Preference and Adherence, 2021
L A Visser,1 M De Mul,2 W K Redekop1 1Health Technology Assessment, Erasmus School of Health Policy & Management, Erasmus University Rotterdam, Rotterdam, the Netherlands; 2Health Services Management & Organization, Erasmus School of Health ...
Visser LA, De Mul M, Redekop WK
doaj  

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