RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Ryanodine receptors: physiological function and deregulation in Alzheimer disease [PDF]
, 2014 BackgroundHealth-care professionals have a responsibility to be attentive to patients’ adherence behavior but it could be difficult to identify poor adherence in the context of clinical practice.
Axelsson, Malin +3 more
core +2 more sources
Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
FEBS Open Bio, EarlyView.To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
Medication Non-Adherence in Anxiety and Depression
Journal of Islamic International Medical College, 2021 Objective :To find out the frequency of non-adherence in patients with anxiety and depression, receiving treatment in teaching hospitals. Study Design: A cross-sectional descriptive study Place and Duration of Study: The study was conducted at Pakistan ...
Masood Khokhar, Shafaq Masood, Ather Muneer, Uzzama Waheed, Farwa Aftab, Irum Bibi
doaj
Using Adherence-Contingent Rebates on Chronic Disease Treatment Costs to Promote Medication Adherence: Results from a Randomized Controlled Trial [PDF]
, 2019 Background: Poor adherence to medications is a global public health concern with substantial health and cost implications, especially for chronic conditions. In the USA, poor adherence is estimated to cause 125,000 deaths and cost $US100 Billion annually.
Bilger, Marcel +6 more
core +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Medication taking behaviour and hypertension: A review of the literature [PDF]
, 2009 Hypertension is a global illness and one that affects circa 20% of the population. Despite the effectiveness of treatment, adherence with medication is a key concern, particularly in the elderly.
Banning, M
core
Impossibility to eliminate observer effect in the assessment of adherence in clinical trials. [PDF]
, 2016 PURPOSE: To utilize the Travoprost Dosing Aid (DA) in the assessment of patient medication adherence, while also determining whether or not altering the functionality of the DA in three randomized subject groups can reduce observer effect. METHODS: Forty-
Fintelmann, Robert E. +6 more
core +3 more sources
Aging and Cancer, EarlyView.ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef +2 more
wiley +1 more source
Self-Assessment of Adherence to Medication: A Case Study in Campania Region Community-Dwelling Population. [PDF]
, 2015 Objectives. The aim of the study was to assess self-reported medication adherence measure in patients selected during a health education and health promotion focused event held in the Campania region. The study also assessed sociodemographic determinants
Colao, Annamaria +7 more
core +5 more sources