Predicting Opioid Use Disorder from Longitudinal Healthcare Data using Multi-stream Transformer [PDF]
Opioid Use Disorder (OUD) is a public health crisis costing the US billions of dollars annually in healthcare, lost workplace productivity, and crime. Analyzing longitudinal healthcare data is critical in addressing many real-world problems in healthcare.
arxiv
Nano‐Anesthetics Regulate Neuro‐Immune Interaction for Treating Neuropathic Pain
Ce‐UiO‐66‐Bupivacaine (CUB) demonstrates triple therapeutic innovation: 1) Sustained analgesia with ROS scavenging synergistically resolves neuropathic pain; 2) Microglia/astrocyte polarization switch reprograms the pro‐regenerative immune microenvironment; 3) CGRP‐TSP‐1 axis activation couples inflammation suppression to axon regeneration, defining a ...
Yue Wang+9 more
wiley +1 more source
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
Hepatology, EarlyView.
Robert J. Fontana+6 more
wiley +1 more source
Systematic Review of Medications for Opioid Use Disorder in Pregnancy within US Prisons and Jails [PDF]
The prevalence of perinatal opioid use disorder (OUD) in the criminal legal system continues to increase, but access to medication for opioid use disorder (MOUD) continues to vary widely throughout the system.
Song, Paige
core +4 more sources
Background Substance use disorder treatment and recovery support services are critical for achieving and maintaining recovery. There are limited data on how structural and social changes due to the COVID-19 pandemic impacted individual-level experiences ...
Eshan U. Patel+7 more
doaj +1 more source
Patient reported goals for medications for opioid use disorder: A theory of proximal goal attainment
Background: There exist substantial patient barriers to accessing medications for opioid use disorder (MOUD), including travel distance, stigma, and availability of MOUD providers.
Kenneth C. Hohmeier+8 more
doaj
Identifying the Optimal Therapeutic Strategy in the Treatment of Substance Use Disorders: Can Pharmacological Therapies Prevent Relapse in Opioid- and Alcohol-Addicted Patients? [PDF]
The addiction to opioids and alcohol is one of the most significant public health concerns worldwide. One of the current approaches to the treatment of substance use disorders is the use of pharmacological therapy.
Peterkin, Melissa
core
Stigma as a fundamental hindrance to the United States opioid overdose crisis response. [PDF]
Alexander Tsai and co-authors discuss the role of stigma in responses to the US opioid ...
Barnett, Michael L+9 more
core +2 more sources
This work proposes the first perovskite/graphene heterostructure‐based FET biosensor with uniquely biotunable ternary logic gating functionality for the detection of human IL6 cytokines. The biosensor integrates a lateral perovskite‐on‐graphene heterostructure phototransistor with a vertical bio‐nano‐photonic filter, achieving ultrahigh sensitivity ...
Jiaxing Sun+7 more
wiley +1 more source
This study details the adaptations required to establish a long‐term anesthetic protocol in pigs. Three protocols were evaluated, with some causing malignant hyperthermia, hypoglycemia, or hemoynamic instability. The final protocol proved effective for developing a porcine AKI model requiring adequate arterial pressure maintenance.
Axel Guilpin+9 more
wiley +1 more source