Results 151 to 160 of about 88,182,083 (298)

Patients with opioid use disorder choosing treatment with extended-release naltrexone: a 6-month naturalistic study.

INTRODUCTION: The treatment efficacy of extended-release naltrexone (XR-NTX) for opioid use disorder (OUD) has been demonstrated in several studies, but not in naturalistic settings where opioid agonist treatment (OAT) is freely accessible.
Tanum, Lars, Mordal, Jon, Løberg, Else-Marie, Solli, Kristin K, Waleur, Karin Merethe, Brenna, Ida Halvorsen, Weimand, Bente, Benth, Jūratė Šaltytė   +7 more
core   +1 more source

Stress-evoked opioid release inhibits pain in major depressive disorder [PDF]

, 2008
To determine whether stress-evoked release of endogenous opioids might account for hypoalgesia in major depressive disorder (MDD), the μ-opioid antagonist naltrexone (50 mg) or placebo was administered double-blind to 24 participants with MDD and to 31 ...
Frew, A.K., Drummond, P.D.
core  

Opioid-use disorder among patients on long-term opioid therapy: impact of final DSM-5 diagnostic criteria on prevalence and correlates

, 2015
Joseph A Boscarino,1 Stuart N Hoffman,1 John J Han2 1Center for Health Research, 2Department of Pain Medicine, Geisinger Clinic, Danville, PA, USAAims: Previously, we estimated the prevalence and risk factors for prescription opioid-use disorder among ...
John Han, Joseph Boscarino, Stuart Hoffman, Hoffman SN, Boscarino JA, Han JJ   +5 more
core   +1 more source

Nail Surgery in Children: Specific Challenges and Practical Considerations

JEADV Clinical Practice, EarlyView.
ABSTRACT Nail surgery in children represents a specific field within dermatologic surgery. Although the procedures themselves are largely similar to those performed in adults, the indications, technical constraints, and perioperative management differ substantially. Pediatric nail disorders are often clinically recognizable, which frequently limits the
F. Lamoline, B. Richert
wiley   +1 more source

Liposomal Bupivacaine Versus Ropivacaine in Combined Thoracic Paravertebral Block and Serratus Anterior Plane Block for Thoracoscopic Surgery: A Randomized Controlled Trial

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The study aimed to compare the use of liposomal bupivacaine (LB) and ropivacaine hydrochloride (RH) in combined thoracic paravertebral block (TPVB) and serratus anterior plane block (SAPB) during video‐assisted thoracoscopic surgery (VATS).
Lu Jin, Lian Tang
wiley   +1 more source

Pharmacy-level barriers to opioid overdose prevention: availability and accessibility of naloxone and buprenorphine–naloxone in high-risk Texas counties

Harm Reduction Journal
Background Texas has experienced a dramatic increase in unintentional opioid deaths over the past decade, underscoring the urgent need for effective prevention strategies.
Kyce G. Darouiche, Moosa M. Malik, Maegan T. Mohr, Michelle A. Hagenimana, Biai D. E. Digbeu, Kathryn A. Cunningham, N. Miles Farr, Carlos R. Dostal   +7 more
doaj   +1 more source

Plasma and Synovial Fluid VEGF‐A and Neuropilin‐1 in Knee Osteoarthritis: Associations With Radiographic Severity, Pain Sensitization‐Related Features, and Disease Burden

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to investigate associations of plasma and synovial fluid vascular endothelial growth factor A (VEGF‐A) and neuropilin‐1 (NRP1) levels with radiographic severity, pain sensitization‐related features, and disease burden in knee osteoarthritis (KOA). Plasma VEGF‐A and NRP1 were measured by sandwich ELISA in 120 patients with KOA (
Cheng‐Ju Tan
wiley   +1 more source

Medication transitions and predictors of illicit substance use during opioid agonist treatment: a three-year follow-up study

Addiction Science & Clinical Practice
Background For opioid use disorder (OUD), pharmacological therapy using methadone or buprenorphine, plus psychosocial support, is the most effective opioid agonist treatment (OAT).
Nina Jobling, Kristian Mjåland, Thomas Clausen, Anne Taraldsen Heldal, Birgitte Thylstrup, John-Kåre Vederhus   +5 more
doaj   +1 more source

Artificial intelligence across the continuum of care for the aging musculoskeletal patient: From longitudinal phenotyping to personalized surgery and recovery monitoring

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Musculoskeletal care is being reshaped by population aging, multimorbidity, frailty, osteoporosis, sarcopenia, polypharmacy and increasing vulnerability to postoperative loss of independence. Artificial intelligence (AI) has entered orthopaedic research, but its clinical translation remains constrained. Many models address isolated diagnostic,
Felix C. Oettl, Balint Zsidai, James A. Pruneski, Jacob F. Oeding, Umile Giuseppe Longo, Michael T. Hirschmann, Ro Du Hyun, Kristian Samuelsson, ESSKA Artificial Intelligence Committee   +8 more
wiley   +1 more source

Cannabis Use and Prolonged Opioid Utilization After Head and Neck Free Flap Reconstructive Surgery

The Laryngoscope, EarlyView.
ABSTRACT Goal This study investigates the risk of prolonged postoperative opioid use and functional outcomes of free flap reconstruction in head and neck cancer patients with a history of cannabis use. Methods Patients undergoing head and neck free flap reconstruction (2005–2025) were identified using the TriNetX database and stratified by cannabis use.
Ella P. Jackert, Tyler Gallagher, Mmasiolu Gamero, Zachary Thompson, Albert Li, Niels C. Kokot   +5 more
wiley   +1 more source