Oxytocin Reduces Noradrenergic-Induced Opioid-Like Withdrawal Symptoms in Individuals on Opioid Agonist Therapy [PDF]
Biological Psychiatry Global Open ScienceBackground: Intranasal administration of the neuropeptide oxytocin has been explored as a potential therapeutic agent for substance use disorder including opioid use disorder (OUD).
Brian J. Gully +7 more
doaj +4 more sources
Inability to contact opioid agonist therapy prescribers during the COVID-19 pandemic in a Canadian setting: a cross-sectional analysis among people on opioid agonist therapy [PDF]
Addiction Science & Clinical Practice, 2022 Background The COVID-19 pandemic and consequent public health response may have undermined key responses to the protracted drug poisoning crisis, including reduced access to opioid agonist therapy (OAT) among people with opioid use disorder.
Soroush Moallef +8 more
doaj +4 more sources
Initiation of opioid agonist therapy after hospital visits for opioid poisonings in Ontario. [PDF]
CMAJ, 2023 Emergency department visits and hospital admissions for opioid toxicity are opportunities to initiate opioid agonist therapy (OAT), which reduces morbidity and mortality in patients with opioid use disorder (OUD). The study objectives were to evaluate OAT initiation rates after a hospital encounter for opioid toxicity in Ontario, Canada, and determine ...
Hu T +7 more
europepmc +3 more sources
Precautions in the management of opioid agonist therapy: from target population characteristics to new formulations and post-marketing monitoring – a focus on the Italian system [PDF]
Drugs in Context, 2023 Opioid use disorder (OUD) is a serious medical condition with vast social, health and economic impact. Individuals with OUD are prescribed opioid agonist therapies, such as methadone, levomethadone, buprenorphine or naloxone/buprenorphine, to reduce the ...
Guido Mannaioni, Fabio Lugoboni
doaj +2 more sources
Breastfeeding on Injectable Opioid Agonist Therapy: A Case Report. [PDF]
J Addict Med, 2023 Background Injectable opioid agonist therapy (iOAT) is the highest-intensity treatment currently available in Canada for individuals with severe opioid use disorder. However, there is limited data on iOAT administration in the perinatal period, with no research, practice guidelines, or known reports of breastfeeding on iOAT ...
Patricelli CJ +8 more
europepmc +3 more sources
Trajectories of retention in opioid agonist therapy in a Canadian setting
International Journal of Drug Policy, 2020 Long-term engagement in opioid agonist therapy (OAT) has been consistently associated with reduced risk for morbidity and mortality in people with opioid use disorder (OUD). However, the dynamic nature of engagement/disengagement in OUD care for over time is poorly captured by traditional metrics. We characterized long-term longitudinal trajectories of
M Eugenia Socias +2 more
exaly +5 more sources
Association of opioid agonist therapy with the initiation of antiretroviral therapy - a systematic review [PDF]
International Journal of Infectious Diseases, 2016 People who inject drugs are at high risk of HIV infection but often face barriers in accessing medical care including access to antiretroviral therapy (ART). Evidence is available about the effectiveness of opioid agonist therapy on drug dependency and risk behaviors.
Bruno F Sunguya, Junkô Yasuoka
exaly +3 more sources
Opioid analgesics for chronic noncancer pain in patients prescribed opioid agonist therapy or with opioid use disorder: A systematic review [PDF]
Canadian Journal of PainBackground Opioid use disorder (OUD) is a growing public health concern in North America, often coexisting with chronic noncancer pain (CNCP). Managing both conditions presents unique challenges, highlighting the need for evidence to guide decision ...
Vahid Ashoorion +9 more
doaj +2 more sources
A qualitative study of experiences with physical activity among people receiving opioid agonist therapy [PDF]
Substance Abuse Treatment, Prevention, and PolicyBackground Physical or mental health comorbidities are common among people with substance use disorders undergoing opioid agonist therapy. As both a preventive and treatment strategy, exercise offers various health benefits for several conditions ...
Einar Furulund +5 more
doaj +2 more sources
Drug and Alcohol Dependence, 2021 Medicaid recipients have a high burden of opioid overdose and opioid use disorder (OUD). Opioid agonist therapies are an effective treatment for OUD, but there is a wide and persisting gap between those who are indicated and those who receive treatment.
Alexandria Macmadu +2 more
exaly +3 more sources