Results 1 to 10 of about 2,872,365 (306)
Key Points Question Can an integrated intervention combining nicotine replacement and brief behavioral support reduce the number of cigarettes smoked among patients receiving opioid agonist therapy?
Druckrey-Fiskaaen KT +7 more
europepmc +3 more sources
Trajectories of retention in opioid agonist therapy in a Canadian setting
Background: Long-term engagement in opioid agonist therapy (OAT) has been consistently associated with reduced risk for morbidity and mortality in people with opioid use disorder (OUD).
Lindsey Richardson +2 more
exaly +6 more sources
Integrated exercise program in opioid agonist therapy clinics and effect on psychological distress: study protocol for a randomized controlled trial (BAReAktiv) [PDF]
Background Substance use disorder is associated with unhealthy lifestyle choices, resulting in adverse social and health consequences. People with opioid use disorder receiving opioid agonist therapy, in particular, have high morbidity and reduced ...
Einar Furulund +9 more
doaj +3 more sources
Comparing Canadian and United States opioid agonist therapy policies
Canada and the United States (U.S.) face an epidemic of opioid use disorder (OUD) and opioid overdose. The most effective OUD treatment is opioid agonist therapy (OAT)—buprenorphine (with and without naloxone) and methadone. Although federal approval for
Lauren Renee Gorfinkel +2 more
exaly +5 more sources
Background The coronavirus pandemic resulted in many changes which had the potential to impact mortality related to opioid agonist therapy (OAT; methadone, buprenorphine), including changes in the prescribing and dispensing of OAT and patterns of drug ...
Nicola J. Kalk +2 more
exaly +2 more sources
Background Moral conservatism within government and communities has resulted in a reluctance to support the provision of opioid agonist therapy for people with opioid use disorders in South Africa. In April 2017, South Africa’s first low-threshold opioid
Monique Marks +2 more
doaj +2 more sources
Background Crystal methamphetamine use has substantially increased among people who use opioids in recent years, yet the impact of opioid agonist therapy (OAT) on crystal methamphetamine use remains poorly characterized.
Thomas Kerr +2 more
exaly +2 more sources
The Dose-Response Relationship between Opioid Agonist Therapy and Alterations in Pain Pathways in Patients with Opioid Use Disorders: A Cross-Sectional Study. [PDF]
The administration of opioids can be followed by enduring neuroplastic changes in the peripheral and central nervous systems. This remodeling can lead to opioid-induced hyperalgesia, causing an increased sensitivity to painful stimuli. The description of
Lang-Illievich K +6 more
europepmc +2 more sources
Opioid analgesics for chronic noncancer pain in patients prescribed opioid agonist therapy or with opioid use disorder: A systematic review [PDF]
Background Opioid use disorder (OUD) is a growing public health concern in North America, often coexisting with chronic noncancer pain (CNCP). Managing both conditions presents unique challenges, highlighting the need for evidence to guide decision ...
Vahid Ashoorion +9 more
doaj +2 more sources
Background Although previous studies have shown that opioid agonist therapy (OAT) is linked to reductions in illicit opioid use, less is known about how OAT impacts the use of other psychoactive substances.
Hubert Wong, Evan Wood, Thomas Kerr
exaly +2 more sources

