Results 41 to 50 of about 22,201 (271)
Addiction Science & Clinical Practice, 2023 Background Hospitalizations are a vital opportunity for the initiation of life-saving opioid agonist therapy (OAT) for patients with opioid use disorder.
John P. Murray +5 more
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Diels–Alder Adducts of Morphinan-6,8-Dienes and Their Transformations
Molecules, 2022 6,14-ethenomorphinans are semisynthetic opiate derivatives containing an ethylene bridge between positions 6 and 14 in ring-C of the morphine skeleton that imparts a rigid molecular structure.
János Marton +5 more
doaj +1 more source
Benefits people experiencing opioid use disorder derive from opioid agonist therapies [PDF]
, 2021 Opioid use disorder has become an epidemic over the past 20 years. Contamination of the street sourced drug supply with fentanyl and fentanyl analogues has resulted in a substantial increase in the associated overdose rate.
core +1 more source
BUPRENORPHINE IN OPIOID ADDICTION TEREATMENT: STUDIES WITH METHADONE COMPARISON
Psychiatry and Clinical Psychopharmacology, 2021 Methadone maintenance treatment is the most widely used pharmacological treatment approach for opioid addiction in many countries. In spite of many benefits that was gained after the usage of full agonist methadone, especially high numbers of patients ...
E.Cüneyt Evren +3 more
doaj
Repurposed oral tapentadol as an intravenous drug of abuse in opioid dependence
Telangana Journal of Psychiatry, 2022 We present to you a case series of a group of individuals who presented to us with a history of intravenous drug abuse of repurposed oral tapentadol. Tapentadol is a synthetic benzenoid with a dual mode of action, as an agonist for the μ-opioid receptor ...
Arshiya Fathima +3 more
doaj +1 more source
BMC Health Services Research, 2019 Background Although opioid agonist therapy is effective in treating opioid use disorders (OUD), retention in opioid agonist therapy is suboptimal, in part, due to quality of care issues. Therefore, we sought to describe the planning and implementation of
Laura Beamish +7 more
doaj +1 more source
HCV elimination in a Swiss opioid agonist therapy programme – a cohort study
Swiss Medical Weekly, 2022 BACKGROUND: In opioid agonist therapy (OAT) programmes, chronic hepatitis C is highly prevalent and directly observed therapy guarantees optimal adherence. Since 2017, all patients with chronic hepatitis C in Switzerland can be treated with pangenotypic direct-acting antivirals irrespective of liver fibrosis stage.
Bregenzer, Andrea +4 more
openaire +3 more sources
A social ecological model (SEM) to exploring barriers of and facilitators to the implementation of Opioid Agonist Treatment (OAT) programmes in prisons [PDF]
, 2021 First paragraph: Opioid agonist treatment (OAT), an evidence-based treatment for opioid dependence, has been associated with reductions in illicit drug use, injecting drug use, the sharing of injecting equipment and an increase in adherence to ...
Komalasari, Rita +2 more
core +1 more source
PLoS Medicine, 2022 Background The overdose crisis in North America has prompted system-level efforts to restrict opioid prescribing for chronic pain. However, little is known about how discontinuing or tapering prescribed opioids for chronic pain shapes overdose risk ...
Mary Clare Kennedy +7 more
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Association of Opioid Agonist Therapy With Lower Incidence of Hepatitis C Virus Infection in Young Adult Injection Drug Users [PDF]
, 2014 IMPORTANCE: Injection drug use is the primary mode of transmission for hepatitis C virus (HCV) infection. Prior studies suggest opioid agonist therapy may reduce the incidence of HCV infection among injection drug users; however, little is known about ...
Page, Kimberly +4 more
core +1 more source