Results 101 to 110 of about 199,052 (264)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Population Pharmacokinetics of Tranexamic Acid in Chinese Population Undergoing Cardiac Surgery with Cardiopulmonary Bypass

open access: yesDrug Design, Development and Therapy
Yue Liu,1 Chenghui Zhou,2 Hong Lv,1 Lei Tian,3 Juanjuan Jiang,3 Jia Shi1 1Department of Anesthesiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and ...
Liu Y   +5 more
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Understandings and social practices of medications for Zimbabwean households in New Zealand

open access: yes, 2011
Medications are a central part of health care. How medications are understood and used by people in everyday life remains unclear. This study looks at understanding and social practices of medications in everyday life for Zimbabwean households in New ...
Groot, Shiloh Ann Maree   +3 more
core  

Subcutaneous hydration and medications infusions (effectiveness, safety, acceptability): A systematic review of systematic reviews.

open access: yes, 2020
ObjectiveTo synthesize the current evidence for subcutaneous hydration and medication infusions from systematic reviews and to assess their methodological quality.IntroductionPeripheral intravascular cannula/catheter insertion is a common invasive ...
Marie Cooke   +7 more
core   +1 more source

Medical libraries and medical research

open access: yesAcademic Medicine, 1966
Presented at the Billings Centennial at the National Library of Medicine in Bethesda, MD. Fogarty reminded his audience of Billings' role in early federal support of research as well as in the growth of the Surgeon General's Library, and then discussed the urgent need for better medical library systems that could keep the growing volume of ...
openaire   +3 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Prescribed medicines for elderly frail people with diabetes resident in nursing homes : issues of polypharmacy and medication costs [PDF]

open access: yes, 2011
Aims To describe the numbers and costs of medications prescribed to people living with diabetes resident in nursing homes in one primary care trust in the UK. Methods A retrospective case notes review of 75 people with known diabetes who were resident in
A. Sinclair   +11 more
core   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

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