Results 121 to 130 of about 199,052 (264)

Use patterns of over-the-counter (OTC) medications and perspectives on OTC medications among Korean adult patients with chronic diseases: gender and age differences

, 2018
Hyun Jeong Kim,* Young-Mo Yang,* Eun Joo Choi Department of Pharmacy, College of Pharmacy, Chosun University, Gwangju, South Korea *These authors contributed equally to this work Background: A number of symptomatic patients tend to use over-the ...
Choi EJ, Kim HJ, Yang YM
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COMPREHENSIVE TREATMENT OF CHILDREN AND ADOLESCENTS WITH PRADER-WILLI SYNDROME AT CENTRE FOR EDUCATION, REHABILITATION, AND TRAINING CIRIUS KAMNIK

Slovenska pediatrija
Prader-Willi syndrome (PWS) is a complex genomic imprinting disorder of chromosomal region 15q, characterized by hypotonia, feeding problems, and emotional-behavioural problems.
Tina Bregant, Marta Orehek Kirbiš, Teja Bandel-Castro, Andreja Širca Čampa, Primož Kotnik   +4 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

COPD: understanding patients’ adherence to inhaled medications

, 2018
António Duarte-de-Araújo,1–3 Pedro Teixeira,1,2 Venceslau Hespanhol,4,5 Jaime Correia-de-Sousa1,2,6 1Life and Health Sciences Research Institute (ICVS), School of Medicine, University of Minho, Braga, Portugal; 2ICVS/3B’s, PT ...
Teixeira P, Hespanhol V, Correia-de-Sousa J, Duarte-de-Araújo A   +3 more
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Natural Products as NLRP3 Inflammasome Inhibitors: A Review

Molecules
An essential multiprotein complex in the innate immune system is the NOD-like receptor family, pyrin domain-containing 3 (NLRP3) inflammasome. Through the coordination of upstream sensors and the adaptor protein ASC, which converge on the inflammasome ...
Yiyi Lu, Lin Jiang, Peng Ding, Minxi Li, Yanmei Peng, Amanpreet Kaur, Zhiwei Yang, Dian Peng, Sai Jiang   +8 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Prescribe medication…Withdraw medication

Turkish Journal of Gastroenterology, 2016
It may be curious sometimes how in the standard medical practice, our patients come to figure out the aetiology of certain gastrointestinal symptoms, and somehow the consequent pursuing of quick solutions, from a therapeutic point of view.
openaire   +2 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Toward a classification of medications for sleep and circadian rhythm disorders

, 2013
Michael J Thorpy,1 Thomas Roth2,31Sleep-Wake Disorders Center, Montefiore Medical Center, Albert Einstein College of Medicine of Yeshiva University, Bronx, New York, NY, USA; 2University of Michigan School of Medicine, Ann Arbor, 3Sleep Disorders and ...
Thorpy MJ, Roth T
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