Results 131 to 140 of about 1,693,150 (290)
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Transient improvement of urticaria induces poor adherence as assessed by Morisky Medication Adherence Scale-8. [PDF]
, 2015 Poor adherence to medication is a major public health challenge. Here, we aimed to determine the adherence to oral and topical medications and to analyze underlying associated factors using the translated Japanese version of Morisky Medication Adherence ...
Abe, Masatoshi +20 more
core
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Navigating Pregnancy Testing in Chronic Pain Management for Women of Reproductive Age
Journal of Pain ResearchShoran Tamura,1 Swarnima Vardhan,2 Kathryn Breidenbach,3 Naum Shaparin,3 Amaresh Vydyanathan,3 Karina Gritsenko3 1Department of Anesthesiology, Columbia University, New York, NY, USA; 2Department of Anesthesiology, Yale New Haven Health/Bridgeport ...
Tamura S +5 more
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ON CRIMINAL LIABILITY FOR ADULTERATED MEDICATIONS
Russian Journal of Economics and Law, 2011 Having studied the circulation of adulterrated medications in Russia, the author has stated that in prractice these actions are qualified by the Russian Criminal Code not uniformly, and grounded including into the Russian Crimianal Code of the Artice 238.
Y. Klyushkina
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Prediagnosis Insights Into Amyotrophic Lateral Sclerosis: Clinical Symptoms and Medication Use
Journal of Cachexia, Sarcopenia and MuscleBackground Amyotrophic lateral sclerosis (ALS) has a prolonged latency period, though its preclinical characteristics remain poorly understood. This study uses UK Biobank data to explore and compare ALS's pre‐diagnostic features, including symptoms and ...
Chunyang Pang +7 more
doaj +1 more source
O Mundo da SaúdeFalls represent a significant public health issue due to their high prevalence and physical, psychological, and social impacts. Medications that affect balance and motor coordination are modifiable risk factors associated with an increased incidence of ...
Ana Luiza Cardoso Rocha +5 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Infection and Drug ResistancePengyu Zhang,1 Wendi Liu,2 Shu Wang,2 Yuan Wang,3 Han Han2 1The Medical College, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, People’s Republic of China; 2School of Chinese Medicine, Shandong University of Traditional Chinese ...
Zhang P, Liu W, Wang S, Wang Y, Han H
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