Results 11 to 20 of about 1,206,345 (314)

β-caryophyllene, an FDA-Approved Food Additive, Inhibits Methamphetamine-Taking and Methamphetamine-Seeking Behaviors Possibly via CB2 and Non-CB2 Receptor Mechanisms

Frontiers in Pharmacology, 2021
Recent research indicates that brain cannabinoid CB2 receptors are involved in drug reward and addiction. However, it is unclear whether β-caryophyllene (BCP), a natural product with a CB2 receptor agonist profile, has therapeutic effects on ...
Xiang-Hu He, Xiang-Hu He, Ewa Galaj, Guo-Hua Bi, Yi He, Briana Hempel, Yan-Lin Wang, Eliot L. Gardner, Zheng-Xiong Xi   +8 more
doaj   +1 more source

Use of Nanocarriers Containing Antitrypanosomal Drugs for the Treatment of Chagas Disease

Pharmaceuticals, 2023
Chagas disease, caused by the Trypanosoma cruzi parasitic protozoan, is a neglected tropical disease (NTD) of significant incidence in Latin America.
Diogo de Freitas Paiva, Ana Paula dos Santos Matos, Denise de Abreu Garófalo, Tatielle do Nascimento, Mariana Sato de Souza de Bustamante Monteiro, Ralph Santos-Oliveira, Eduardo Ricci-Junior   +6 more
doaj   +1 more source

Effect of Medications in Osseointegration [PDF]

, 2023
Implants have been a modern solution for treating edentulism nowadays. But the effect of certain diseases as well as medications marks a question among the dental practitioners about the survivability of implants.
S Sethulakshmi, Cherian K Philip, Joe Mathew, Alan Joseph   +3 more
core   +1 more source

THE MEDICAL DIRECTORY. [PDF]

The Lancet, 1902
n ...
Churchill, J. AndA, Churchill, J. & A, Churchill, J., Churchill, J.&A, Churchill, A.   +4 more
openaire   +1 more source

Role of efficacy as a determinant of locomotor activation by mu‐opioid receptor (MOR) ligands in female and male mice. II. Effects of novel MOR‐selective phenylmorphans with high‐to‐low MOR efficacy

Pharmacology Research & Perspectives, 2023
Low‐efficacy mu‐opioid receptor (MOR) agonists represent promising therapeutics, but existing compounds (e.g., buprenorphine, nalbuphine) span a limited range of low MOR efficacies and have poor MOR selectivity.
Edna J. Santos, Nima Nassehi, Eric W. Bow, Dana R. Chambers, Eugene S. Gutman, Arthur E. Jacobson, Joshua A. Lutz, Samuel A. Marsh, Kenner C. Rice, Agnieszka Sulima, Dana E. Selley, S. Stevens Negus   +11 more
doaj   +1 more source

Stakeholder perceptions of lethal means safety counseling: A qualitative systematic review

Frontiers in Psychiatry, 2022
IntroductionLethal means safety counseling (LMSC) is an evidence-based suicide prevention intervention during which providers encourage patients to limit their access to lethal means (e.g., firearms, medications).
Gabriela Kattan Khazanov, Shimrit Keddem, Shimrit Keddem, Katelin Hoskins, Karoline Myhre, Sarah Sullivan, Emily Mitchell, Brooke Dorsey Holliman, Sara J. Landes, Sara J. Landes, Joseph Simonetti, Joseph Simonetti   +11 more
doaj   +1 more source

Acute Heart Failure Is a Malignant Process: But We Can Induce Remission

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Acute heart failure is a common and increasingly prevalent condition, affecting >10 million people annually. For those patients who survive to discharge, early readmissions and death rates are >30% everywhere on the planet, making it a malignant ...
Gad Cotter, Beth A. Davison, Carolyn S. P. Lam, Marco Metra, Piotr Ponikowski, John R. Teerlink, Alexandre Mebazaa   +6 more
doaj   +1 more source

Deletion of Type 2 Metabotropic Glutamate Receptor Decreases Sensitivity to Cocaine Reward in Rats

Cell Reports, 2017
Cocaine users show reduced expression of the metabotropic glutamate receptor (mGluR2), but it is not clear whether this is a predisposing trait for addiction or a consequence of drug exposure.
Hong-Ju Yang, Hai-Ying Zhang, Guo-Hua Bi, Yi He, Jun-Tao Gao, Zheng-Xiong Xi   +5 more
doaj   +1 more source

Patient factors associated with new prescribing of potentially inappropriate medications in multimorbid US older adults using multiple medications. [PDF]

, 2021
BACKGROUND The use of potentially inappropriate medications (PIMs) is common in older adults and is associated with potential negative consequences, such as falls and cognitive decline.
Streit, Sven, Jungo, Katharina Tabea, Lauffenburger, Julie C   +2 more
core   +1 more source

Analysis of potential risk factors associated with COVID-19 and hospitalization

Frontiers in Public Health, 2022
Coronavirus disease 2019 (COVID-19) was found to cause complications in certain groups of people, leading to hospitalization. Several factors have been linked to this, such as gender, age, comorbidity, and race.
Abdul-Hakeem Moazi Alharbi, Abdul-Hakeem Moazi Alharbi, Syed Imam Rabbani, Ashraf Abdel Halim Mohamed, Ashraf Abdel Halim Mohamed, Basil Khalid Almushayti, Basil Khalid Almushayti, Nasser Ibrahim Aldhwayan, Nasser Ibrahim Aldhwayan, Ali Tami Almohaimeed, Ali Tami Almohaimeed, Abdullah Abdulrhman Alharbi, Abdullah Abdulrhman Alharbi, Naif Saad Alharbi, Naif Saad Alharbi, Syed Mohammed Basheeruddin Asdaq, Abdulhakeem S. Alamri, Abdulhakeem S. Alamri, Walaa F. Alsanie, Walaa F. Alsanie, Majid Alhomrani, Majid Alhomrani   +21 more
doaj   +1 more source