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The Lived Experience of Medication for Opioid Use Disorder
Abstract Purpose of the Study Buprenorphine and methadone, when used as maintenance therapy in opioid use disorder (OUD), can significantly reduce the risk of death after an opioid overdose. Despite the many benefits, medication for OUD (MOUD) remains controversial and underutilized.
Aimee Techau+3 more
openaire +2 more sources
New Hampshire Baseline Needs Assessment: Barriers to Substance Use Disorder Treatment Data Brief [PDF]
This data brief focuses on practitioners’ and community stakeholders’ reported barriers and challenges to treating patients with opioid use disorder (OUD) and beliefs about treating patients using medications for OUD (MOUD)
Center on Rural Addiction, University of Vermont+1 more
core +1 more source
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman+4 more
wiley +1 more source
Anhedonia modulates benzodiazepine and opioid demand among persons in treatment for opioid use disorder [PDF]
BACKGROUND: Benzodiazepine (BZD) misuse is a significant public health problem, particularly in conjunction with opioid use, due to increased risks of overdose and death.
Greenwald, Mark K+3 more
core +2 more sources
Health disparities in chronic liver disease
Abstract The syndemic of hazardous alcohol consumption, opioid use, and obesity has led to important changes in liver disease epidemiology that have exacerbated health disparities. Health disparities occur when plausibly avoidable health differences are experienced by socially disadvantaged populations.
Ani Kardashian+3 more
wiley +1 more source
Multi-objective Molecular Optimization for Opioid Use Disorder Treatment Using Generative Network Complex [PDF]
Opioid Use Disorder (OUD) has emerged as a significant global public health issue, with complex multifaceted conditions. Due to the lack of effective treatment options for various conditions, there is a pressing need for the discovery of new medications. In this study, we propose a deep generative model that combines a stochastic differential equation (
arxiv
Background Medication treatment for opioid use disorder (OUD) (MOUD; buprenorphine and methadone) reduces opioid use and overdose. Discontinuation of MOUD can quickly lead to relapse, overdose and death.
Breanne E. Biondi+4 more
doaj +1 more source
Machine-learning Analysis of Opioid Use Disorder Informed by MOR, DOR, KOR, NOR and ZOR-Based Interactome Networks [PDF]
Opioid use disorder (OUD) continuously poses major public health challenges and social implications worldwide with dramatic rise of opioid dependence leading to potential abuse. Despite that a few pharmacological agents have been approved for OUD treatment, the efficacy of said agents for OUD requires further improvement in order to provide safer and ...
arxiv
Background: Of the over 20 million Americans reporting an opioid use disorder, only around 3 million report receiving treatment of any kind. The gold standard for opioid use disorder treatment is medication in combination with psychosocial support, but ...
Kenneth C Hohmeier+6 more
doaj +1 more source
Medication Treatment of Active Opioid Use Disorder in Veterans With Cirrhosis
INTRODUCTION: Although opioid use disorder (OUD) is common in patients with cirrhosis, it is unclear how medication treatment for OUD (MOUD) is used in this population. We aimed to assess the factors associated with MOUD and mortality in a cohort of Veterans with cirrhosis and OUD. METHODS:
Rogal, Shari+9 more
openaire +4 more sources