Results 91 to 100 of about 282,673 (304)

The Antidiabetic Activity of Curry Leaves “Murraya Koenigii” on the Glucose Levels, Kidneys, and Islets of Langerhans of Rats with Streptozotocin Induced Diabetes [PDF]

open access: yes, 2017
Background: The aims of this study were to explore the antihyperglycemic effect of curry leaves, Murraya koenigii "MK" aqueous extract, and to examine its possible protective effects on the islets of Langerhans and kidneys of streptozotocin (STZ ...
Al-Ani, I. M. (Imad)   +4 more
core  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Mango, the king of fruits, with fascinating pharmacological activities and medicinal uses

open access: yesOpen Veterinary Journal
Mango (Mangifera sp.; family: Anacardiaceae) is one of the most widely consumed fruits globally due to its rich and aromatic flavor, which is balanced with a pleasant balance of sweetness and acidity.
Hala T. Mahmoud   +4 more
doaj   +1 more source

Historical Roots, Spiritual Significance and the Health Benefits of mKhempa-lJong gNyes Tshachu (hot spring) in Lhuntshe [PDF]

open access: yes, 2007
Bhutan is a country blessed with many rich natural medicinal resources such as minerals, animals, plants, sman-chu (medicinal waters) and tshachu (hot springs).
Dorji, Yeshi, Wangchuk, Phurpa
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Medicinal plants: A source of phytobiotics for the feed additives

open access: yesJournal of Agriculture and Food Research
Medicinal plants are a rich source of secondary metabolites, which can be used in veterinary medicine as growth stimulants and as next-generation antibacterials.
Svetlana Ivanova   +9 more
doaj   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

An empirical assessment of wild fauna species as critical ingredients for traditional curative therapy

open access: yesScientific African
Medicinal practices that incorporate animal parts can strengthen the relationships between people and wildlife. Although this practice is recognised as a positive use of wildlife for healing, the demand for animal-based healing remedies poses a threat to
B.S. OJELADE, W.A. JAYEOBA, J.B.O. OGOLA
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

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