Results 81 to 90 of about 1,562,094 (290)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Laparoscopy in small animal medicine
Veterinary Quarterly, 1985 Laparoscopy is described as a safe, simple, and relatively non-invasive diagnostic technique for the visualization of abdominal organs. The instruments required, the procedure of laparoscopy, and indications and contra-indications are described. The advantages of laparoscopy above laparotomy are discussed.
openaire +2 more sources
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Globalisation and sustainable exports of Indian medicinal and aromatic plants: A protection study [PDF]
India has a rich heritage of traditional systems of medicine viz. Ayurveda, Unani, Siddha, Tibetan which are mostly based on botanical formulations. Although biologically, the region is extremely rich in medicinal plants, due to years of unwise use, the ...
Bera, Soumitra Kumar
core
Medicinal plants for diabetes treatment during pregnancy
, 2017 Diabetes mellitus is a syndrome of great importance that affects an increasing number of people every day. In particular, diabetes is a common and important disease during pregnancy and is marked by complications, both fetal and maternal, that increase ...
Damasceno, Debora Cristina [UNESP] +4 more
core +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Безопасность и риск фармакотерапииSCIENTIFIC RELEVANCE. Currently, there are no effective and safe medicinal products for idiopathic male infertility. Previous studies in two animal models of infertility (short-term cryptorchidism in rats and doxorubicin-induced testicular injury in mice)
A. O. Monakova +9 more
doaj +1 more source
Animals, moral risk and moral considerability [PDF]
, 2007 I believe that accounts of the moral considerability of animals can be strengthened in an interesting and novel way if attention is paid to moral risk and epistemic responsibility.
Tanner, Julia K. H., Tanner, Julia K H
core
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Mango, the king of fruits, with fascinating pharmacological activities and medicinal uses
Open Veterinary JournalMango (Mangifera sp.; family: Anacardiaceae) is one of the most widely consumed fruits globally due to its rich and aromatic flavor, which is balanced with a pleasant balance of sweetness and acidity.
Hala T. Mahmoud +4 more
doaj +1 more source