Results 171 to 180 of about 349,116 (315)

Synthetic Organic Chemistry, Medicinal Chemistry [PDF]

, 2004
松谷 裕二, 根本 英雄, 豊岡 尚樹   +2 more
core   +4 more sources

ACS Journals: Biological and Medicinal Chemistry [PDF]

, 2006

openalex   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source

Medicinal Chemistry: Abstracts 76-120

CHIMIA, 2008
doaj   +1 more source

Expanding Roles for Organoboron Compounds – Versatile and Valuable Molecules for Synthetic, Biological and Medicinal Chemistry [PDF]

, 2007
Nicos A. Petasis
openalex   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Characterization of Opioid Agonist Morphine Derivatives with Emphasis on Medicinal Chemistry. [PDF]

ChemMedChem
Malik A, Hosztafi S, Vincze A, Marton A, Kraszni M, Balogh GT, Noszál B, Mazák K.   +7 more
europepmc   +1 more source

Medicinal Chemistry: Abstracts 56-105

CHIMIA, 2009
doaj   +1 more source

Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae) [PDF]

, 2007
Anita Brinker, Jun Ma, Peter E. Lipsky, Ilya Raskin   +3 more
openalex   +1 more source

The Future of Medicinal Chemistry [PDF]

Angewandte Chemie International Edition, 2012
Rainer Metternich, Torsten Hoffmann
openaire   +3 more sources