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Implementing a Functional Group Analysis Activity to Support Student Learning in Medicinal Chemistry: A Three-Year Experience. [PDF]
Pharmacy (Basel)Belani A, Belani JD.
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Drug Discovery Today, 2006
With the advent of high throughput technologies in biological screening in the 1980s, providing sufficient numbers of small molecules for screening became a bottleneck in the drug discovery process. Combinatorial chemistry was the first attempt by chemists to address this issue. However, since its first applications, combinatorial chemistry has evolved
Marcus, Koppitz, Knut, Eis
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With the advent of high throughput technologies in biological screening in the 1980s, providing sufficient numbers of small molecules for screening became a bottleneck in the drug discovery process. Combinatorial chemistry was the first attempt by chemists to address this issue. However, since its first applications, combinatorial chemistry has evolved
Marcus, Koppitz, Knut, Eis
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Metallocyclodextrins in Medicinal Chemistry
Future Medicinal Chemistry, 2018This review focuses on metal complexes of cyclodextrin (CyD) derivatives designed for application as therapeutics or diagnostics. We discuss examples of metalloprotein models (hemoglobin, superoxide dismutase and catalase) based on cyclodextrins. The hydrophobic microenvironment of CyDs stabilizes the Fe(II) porphyrin system that can reversibly bind O2
Valentina Oliveri, Graziella Vecchio
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Computational Medicinal Chemistry
Journal of Medicinal Chemistry, 2010Martin, Stahl, Jürgen, Bajorath
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Perspectives in Medicinal Chemistry:
Current Topics in Medicinal Chemistry, 2015Guo-Ping, Zhou, Wei-Zhu, Zhong
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