Results 241 to 250 of about 2,645,063 (296)

Imidazo[1,2‑<i>a</i>]pyridines in Medicinal Chemistry: Recent Advances in Synthesis and Biological Activities. [PDF]

ACS Omega
Ferreira LAP, Caruso L, Nadur NF, Franco DP, Sousa GLS, Lacerda RB, Kümmerle AE.   +6 more
europepmc   +1 more source

Session Medicinal Chemistry Chemical Biology

CHIMIA, 2018
David Spichiger
doaj  

Building a Medicinal Chemistry Framework for Bioorthogonal Probes. [PDF]

ACS Cent Sci
Staudt M, Carlson JCT.
europepmc   +1 more source

Crystal Engineering as an Efficient Medicinal Chemistry Tool for Animal PK Bioavailability Enhancement in Early Pre-Clinical Research. [PDF]

Pharmaceuticals (Basel)
Becker A, von Essen C, Burgdorf L, Lecomte M, Bischof D.   +4 more
europepmc   +1 more source

Combined computational and classical medicinal chemistry procedure to disclose novel pyrrole-based compounds as potential antituberculosis agents. [PDF]

J Comput Aided Mol Des
Ragno R, Zwergel C, Valente S, Astolfi R, Lambona C, Proia E, Giuliani L, Franzblau SG, Fioravanti R, Mai A.   +9 more
europepmc   +1 more source

Session Medicinal Chemistry & Chemical Biology

CHIMIA
doaj  

2-Phenethylamines in Medicinal Chemistry: A Review

Molecules, 2023
A concise review covering updated presence and role of 2-phenethylamines in medicinal chemistry is presented. Open-chain, flexible alicyclic amine derivatives of this motif are enumerated in key therapeutic targets, listing medicinal chemistry hits and ...
Narciso Martin Garrido, Alejandro Manchado, David Diez   +2 more
exaly   +2 more sources

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Metallocyclodextrins in Medicinal Chemistry

Future Medicinal Chemistry, 2018
This review focuses on metal complexes of cyclodextrin (CyD) derivatives designed for application as therapeutics or diagnostics. We discuss examples of metalloprotein models (hemoglobin, superoxide dismutase and catalase) based on cyclodextrins. The hydrophobic microenvironment of CyDs stabilizes the Fe(II) porphyrin system that can reversibly bind O2
Valentina Oliveri, Graziella Vecchio
openaire   +3 more sources

The Medicinal Chemistry of Caffeine

Journal of Medicinal Chemistry, 2021
The purine alkaloid caffeine is the most widely consumed psychostimulant drug in the world and has multiple beneficial pharmacological activities, for example, in neurodegenerative diseases. However, despite being an extensively studied bioactive natural product, the mechanistic understanding of caffeine's pharmacological effects is incomplete.
Giuseppe Faudone, Silvia Arifi, Daniel Merk   +2 more
openaire   +2 more sources

Polyethylenimine In Medicinal Chemistry

Current Medicinal Chemistry, 2008
Polyethylenimine (PEI), an organic branched or linear polyamine polymer, has been successfully used in the past for DNA complexation and transfection in vitro and in vivo into several cell lines and tissues. PEI was also applied in different fields from gene therapy and several studies have emphasized the importance of this polymer in medicinal ...
VICENNATI, PAOLA, GIULIANO, ANTONELLA, ORTAGGI, Giancarlo, MASOTTI, ANDREA   +3 more
openaire   +2 more sources