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The impact of click chemistry in medicinal chemistry
Expert Opinion on Drug Discovery, 2012The copper(I)-catalyzed 1,3-dipolar cycloaddition of alkynes and azides to form 1,2,3-triazoles is the most popular reaction in click chemistry. This reaction is also near-perfect, in terms of its robustness, due to the high degree of reliability and complete specificity.
Jingli, Hou +4 more
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Current Medicinal Chemistry, 2014
Over the last centuries, there were many important discoveries in medicine that were crucial for gaining a better understanding of several physiological processes. Molecular modelling techniques are powerful tools that have been successfully used to analyse and interface medicinal chemistry studies with electrochemical experimental results.
M O, Almeida +5 more
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Over the last centuries, there were many important discoveries in medicine that were crucial for gaining a better understanding of several physiological processes. Molecular modelling techniques are powerful tools that have been successfully used to analyse and interface medicinal chemistry studies with electrochemical experimental results.
M O, Almeida +5 more
openaire +2 more sources
2003
In the past decade, nuclear magnetic resonance (NMR) spectroscopy has gained an enormous impact on drug research, due to its extraordinary capacity to measure properties and observe changes at individual atomic positions even in very complex systems. While the analysis of molecular structures still is the main goal of classical NMR investigations, it ...
Kessler, H. +5 more
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In the past decade, nuclear magnetic resonance (NMR) spectroscopy has gained an enormous impact on drug research, due to its extraordinary capacity to measure properties and observe changes at individual atomic positions even in very complex systems. While the analysis of molecular structures still is the main goal of classical NMR investigations, it ...
Kessler, H. +5 more
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Perspectives in Medicinal Chemistry: The Evolution of Medicinal Chemistry
Current Topics in Medicinal Chemistry, 2015J Phillip, Bowen, Haizhen A, Zhong
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Perspectives in Medicinal Chemistry:
Current Topics in Medicinal Chemistry, 2015Guo-Ping, Zhou, Wei-Zhu, Zhong
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Medicinal chemistry strategies towards the development of effective SARS-CoV-2 inhibitors
Acta Pharmaceutica Sinica B, 2022Lin Sun, Dongwei Kang, Tong Zhao
exaly
Lipopeptides as tools in catalysis, supramolecular, materials and medicinal chemistry
Nature Reviews Chemistry, 2023Ignacio Colomer, Cesar Vicente-Garcia
exaly
Click chemistry in medicinal chemistry for Comprehensive medicinal chemistry III
2017P. Thirumurugan, K. Jozwiak
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