Results 281 to 290 of about 376,307 (328)

FEM1B enhances TRAIL‐induced apoptosis in T lymphocytes and monocytes

FEBS Open Bio, EarlyView.
FEM1B facilitates TRAIL‐induced apoptosis through distinct mechanisms in T lymphocytes and monocytes. In T lymphocytes, FEM1B engages with TRAF2, leading to a reduction in TRAF2 expression, which subsequently lessens TRAF2's inhibitory influence on caspase‐8.
Chenbo Yang, Wenhui Yu, Cui Dang, Jingjing Zhang, Jiahan Lu, Jing Xue   +5 more
wiley   +1 more source

Empowering Voices: Inspiring Women in Medicinal Chemistry. [PDF]

ACS Med Chem Lett
Blanco MJ, Bronson JJ, DiMauro EF, Dzierba C, Eggen M, Garner AL, Georg G, Giarolla J, Goodwin NC, Grenier-Davies MC, Haskell-Luevano C, Holzgrabe U, Huang R, Lagiakos HR, Leftheris K, Martin Y, Matos MJ, May-Dracka TL, Müller CE, Newman AH, Parmee E, Petter JC, Tamayo NA, Wexler RR, Bolognesi ML, Ripka A, Young W.   +26 more
europepmc   +1 more source

Total Synthesis as Training for Medicinal Chemistry. [PDF]

ACS Med Chem Lett
Pennington LD.
europepmc   +1 more source

ERAP Inhibitors in Autoimmunity and Immuno-Oncology: Medicinal Chemistry Insights. [PDF]

J Med Chem
Fougiaxis V, He B, Khan T, Vatinel R, Koutroumpa NM, Afantitis A, Lesire L, Sierocki P, Deprez B, Deprez-Poulain R.   +9 more
europepmc   +1 more source

Accelerating the Hit-To-Lead Optimization of a SARS-CoV-2 Mpro Inhibitor Series by Combining High-Throughput Medicinal Chemistry and Computational Simulations. [PDF]

J Med Chem
Hazemann J, Kimmerlin T, Mac Sweeney A, Bourquin G, Lange R, Ritz D, Richard-Bildstein S, Regeon S, Czodrowski P.   +8 more
europepmc   +1 more source

2-Heteroarylethylamines in medicinal chemistry: a review of 2-phenethylamine satellite chemical space. [PDF]

Beilstein J Org Chem
Nieto C, Manchado A, García-González Á, Díez D, Garrido NM.   +4 more
europepmc   +1 more source

Regioselective Nucleophilic Aromatic Substitution: Theoretical and Experimental Insights into 4-Aminoquinazoline Synthesis as a Privileged Structure in Medicinal Chemistry. [PDF]

Molecules
Barbosa MLC, Pinheiro PSM, Alves da Conceição R, Pires JR, Franco LS, Sant'Anna CMR, Barreiro EJ, Lima LM.   +7 more
europepmc   +1 more source

Expression of Concern: Activation of protein phosphatase 2A tumor suppressor as potential treatment of pancreatic cancer

Molecular Oncology, EarlyView.
wiley   +1 more source