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Synthetic strategies and medicinal chemistry perspectives of dual acting carbonic anhydrase modulators with monoamine oxidase and cholinesterase inhibitors. [PDF]
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Furazans in Medicinal Chemistry.
Journal of Medicinal Chemistry, 2021Incorporation of heterocycles into drug molecules can enhance physical properties and biological activity. A variety of heterocyclic groups is available to medicinal chemists, many of which have been reviewed in detail elsewhere.
Ross S. Mancini +3 more
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Chemistry, 2022
Extension of the medicinal chemistry toolbox is in the vital interest of drug designers. However, the diffusion of an innovation can be a lengthy process.
U. Lücking
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Extension of the medicinal chemistry toolbox is in the vital interest of drug designers. However, the diffusion of an innovation can be a lengthy process.
U. Lücking
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Benzoxazine: a privileged scaffold in medicinal chemistry.
Current Medicinal Chemistry, 2022BACKGROUND Benzoxazine is one of the most important privileged scaffolds in medicinal chemistry. Compounds bearing benzoxazine moiety usually have a variety of biological activities, such as anti-inflammatory, anti-microbial, anti-tuberculosis, anti ...
Zilong Tang +3 more
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The Medicinal Chemistry of Caffeine.
Journal of Medicinal Chemistry, 2021The purine alkaloid caffeine is the most widely consumed psychostimulant drug in the world and has multiple beneficial pharmacological activities, for example, in neurodegenerative diseases. However, despite being an extensively studied bioactive natural
Giuseppe Faudone, Silvia Arifi, D. Merk
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Asymmetric organocatalysis: an enabling technology for medicinal chemistry.
Chemical Society Reviews, 2021The efficacy and synthetic versatility of asymmetric organocatalysis have contributed enormously to the field of organic synthesis since the early 2000s.
Bo Han +5 more
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Recent Advances in the Medicinal Chemistry of Farnesoid X Receptor.
Journal of Medicinal Chemistry, 2021Farnesoid X receptor (FXR) is an important regulator of bile acid, lipid, amino acid, and glucose homeostasis, hepatic inflammation, regeneration, and fibrosis.
Yuanying Fang +3 more
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