Results 41 to 50 of about 2,645,063 (296)
Assessing the impact of clinically relevant medicinal chemistry teaching: Learning gains from case study approach [PDF]
Brazilian Journal of Pharmaceutical SciencesConsidering the unique role of medicinal chemistry in the pharmacists’ formation, in this work we assessed the impact of medicinal chemistry teaching on the interpretation of a clinical situation using statistical and learning gain analysis.
Fernanda Domingues Lustoza +1 more
doaj +1 more source
Molecular Filters in Medicinal Chemistry
Encyclopedia, 2023 Efficient chemical library design for high-throughput virtual screening and drug design requires a pre-screening filter pipeline capable of labeling aggregators, pan-assay interference compounds (PAINS), and rapid elimination of swill (REOS); identifying
Sebastjan Kralj +2 more
doaj +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–6
Molecules, 2019 Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes is a series of Editorials that is published on a biannual basis by the Editorial Board of the Medicinal Chemistry section of the journal Molecules [...]
Jean Jacques Vanden Eynde +41 more
doaj +1 more source
Open Medicinal Chemistry [PDF]
ChemMedChem, 2018 Hello 2019! ChemMedChem Editor David Peralta looks back at the journal's activities in 2018, as well as upcoming Special Collections, features, and developments for ChemPubSoc Europe in 2019. He also introduces the journal's new Editorial Board co-chair, Prof. Sangyong Jon from the Korea Advanced Institute of Science and Technology (KAIST).
openaire +2 more sources
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Women in Medicinal Chemistry Special Issue Call for Papers
, 2019 The Journal of Medicinal Chemistry will be publishing a special issue on “Women in Medicinal Chemistry” in March 2020 together with ACS Medicinal Chemistry Letters, publishing on the same topic.Full ...
Hong Liu +11 more
core +1 more source
, 2022 Azulene is a bicyclic scaffold rarely applied in medicinal chemistry. Here we report physicochemical and in vitro parameters relevant for drug discovery for a series of diversely substituted azulenes.
Wallén, Erik A. A. +6 more
core +1 more source
Anti-Cancer Agents in Medicinal Chemistry
, 2013 Anti-Cancer Agents in Medicinal Chemistry aims to cover all the latest and outstanding developments in medicinal chemistry and rational drug design for the discovery of anti-cancer agents.
CAPRANICO, GIOVANNI
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source