Results 21 to 30 of about 3,137,400 (295)
Molecules, 2021 During the last few decades, pyridazine derivatives have emerged as privileged structures in heterocyclic chemistry, both because of their excellent chemistry and because of their potential applications in medicinal chemistry and optoelectronics.
Dorina Amariucai-Mantu +2 more
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Medicinal Chemistry of Isocyanides [PDF]
Chemical Reviews, 2021 In eons of evolution, isocyanides carved out a niche in the ecological systems probably thanks to their metal coordinating properties. In 1859 the first isocyanide was synthesized by humans and in 1950 the first natural isocyanide was discovered. Now, at the beginning of XXI century, hundreds of isocyanides have been isolated both in prokaryotes and ...
Alberto Massarotti +4 more
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Looking back and moving forward in medicinal chemistry
Nature Communications, 2023 Medicinal chemistry is a fast-evolving interdisciplinary research area which aims to improve human life by developing drugs to combat diseases. Nature Communications interviewed three scientists, Daniele Castagnolo (Associate Professor at University ...
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Oxazolidinones as versatile scaffolds in medicinal chemistry
, 2023 Oxazolidinone is a five-member heterocyclic ring with several biological applications in medicinal chemistry. Among the three possible isomers, 2-oxazolidinone is the most investigated in drug discovery. Linezolid was pioneered as the first approved drug
Cauê Benito Scarim +9 more
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Metal Complexes and Medicine: A Successful Combination
CHIMIA, 2015 Since the start of our independent research at the Department of Chemistry of the University of Zurich in 2009, our group has been, among other topics, working on the use of metal complexes in medicinal chemistry.
Gilles Gasser
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Cubanes in Medicinal Chemistry
Journal of Medicinal Chemistry, 2018 Cubane is a highly strained saturated hydrocarbon system that has historically been of interest in theoretical organic chemistry. More recently it has become a molecule of interest for biological applications due to its inherent stability and limited toxicity.
Reekie, TA +3 more
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An Element of Community: EFMC, the European Federation for Medicinal Chemistry
CHIMIA, 2019 The Division of Medicinal Chemistry and Chemical Biology of the Swiss Chemical Society is an active member of the European Federation for Medicinal Chemistry (EFMC), whose mission is to advance the science of medicinal chemistry in Europe. EFMC promotes
Yves P. Auberson
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Women in Medicinal Chemistry: Ad Maiora! (Editorial)
, 2020 Journal of Medicinal Chemistry is proud to share the release of its first special issue dedicated to “Women in Medicinal Chemistry”, jointly published with ACS Medicinal Chemistry Letters.No Full ...
Ganamet, Kelly L +5 more
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Click Reactions in Medicinal Chemistry
Pharmaceuticals, 2023 Two decades after K [...]
Damien Bosc
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