Results 21 to 30 of about 2,645,063 (296)
, 2022 The field of medicinal (organic, bioinorganic, and coordination) chemistry as well as the interdisciplinary studies related to medicine is a rapidly developing area of study [...
Kostova, Irena, Irena Kostova
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Synthesis of cyclic peptides and peptidomimetics by metathesis reactions [PDF]
, 2015 This review surveys developments in the field of ring-closing metathesis and cross-metathesis reactions applied to the synthesis of constrained amino acids, peptides, and peptidomimetics.
Rijkers, D.T.S. +3 more
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Epigenetic Medicinal Chemistry [PDF]
ACS Medicinal Chemistry Letters, 2015 The past decade has seen tremendous growth in our understanding of epigenetics and chromatin remodeling. Small, organic molecule modulators of a number of chromatin modifying proteins (CMPs) have been reported over this time frame and several of these have advanced to human clinical trials.
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Miniproteins in medicinal chemistry
Bioorganic & Medicinal Chemistry Letters, 2022 Miniproteins exhibit great potential as scaffolds for drug candidates because of their well-defined structure and good synthetic availability. Because of recently described methodologies for their de novo design, the field of miniproteins is emerging and can provide molecules that effectively bind to problematic targets, i.e., those that have been ...
Agnieszka, Ciesiołkiewicz +2 more
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Women in Medicinal Chemistry: Ad Maiora! (Editorial)
, 2020 Journal of Medicinal Chemistry is proud to share the release of its first special issue dedicated to “Women in Medicinal Chemistry”, jointly published with ACS Medicinal Chemistry Letters.No Full ...
Ganamet, Kelly L +5 more
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, 2022 In this review, the history of boron’s early use in drugs, and the history of the use of boron functional groups in medicinal chemistry applications are discussed.
Katia Messner +2 more
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Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–7
Molecules, 2020 Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes is a series of editorials which is published on a biannual basis by the Editorial Board of the Medicinal Chemistry section of the journal Molecules [...]
Michael Gütschow +47 more
doaj +1 more source
Medicinal Chemistry for 2020 [PDF]
Future Medicinal Chemistry, 2011 Rapid advances in our collective understanding of biomolecular structure and, in concert, of biochemical systems, coupled with developments in computational methods, have massively impacted the field of medicinal chemistry over the past two decades, with even greater changes appearing on the horizon.
Seetharama D, Satyanarayanajois +1 more
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Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito +7 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
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