Results 11 to 20 of about 397,906 (291)
Epigenetic Medicinal Chemistry [PDF]
ACS Medicinal Chemistry Letters, 2015 The past decade has seen tremendous growth in our understanding of epigenetics and chromatin remodeling. Small, organic molecule modulators of a number of chromatin modifying proteins (CMPs) have been reported over this time frame and several of these have advanced to human clinical trials.
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Looking back and moving forward in medicinal chemistry
Nature Communications, 2023 Medicinal chemistry is a fast-evolving interdisciplinary research area which aims to improve human life by developing drugs to combat diseases. Nature Communications interviewed three scientists, Daniele Castagnolo (Associate Professor at University ...
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BindingDB in 2015: A public database for medicinal chemistry, computational chemistry and systems pharmacology. [PDF]
, 2015 BindingDB, www.bindingdb.org, is a publicly accessible database of experimental protein-small molecule interaction data. Its collection of over a million data entries derives primarily from scientific articles and, increasingly, US patents.
Baitaluk, Michael +5 more
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Open Medicinal Chemistry [PDF]
ChemMedChem, 2018 Hello 2019! ChemMedChem Editor David Peralta looks back at the journal's activities in 2018, as well as upcoming Special Collections, features, and developments for ChemPubSoc Europe in 2019. He also introduces the journal's new Editorial Board co-chair, Prof. Sangyong Jon from the Korea Advanced Institute of Science and Technology (KAIST).
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Metal Complexes and Medicine: A Successful Combination
CHIMIA, 2015 Since the start of our independent research at the Department of Chemistry of the University of Zurich in 2009, our group has been, among other topics, working on the use of metal complexes in medicinal chemistry.
Gilles Gasser
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Development of Advanced Macrosphelides: Potent Anticancer Agents
Molecules, 2015 Synthetic approaches to macrosphelide derivatives, based on medicinal chemistry, are summarized. This review contains conventional medicinal chemistry approaches, combinatorial chemistry, fluorous tagging techniques and affinity chromatography ...
Seung-Mann Paek
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An Element of Community: EFMC, the European Federation for Medicinal Chemistry
CHIMIA, 2019 The Division of Medicinal Chemistry and Chemical Biology of the Swiss Chemical Society is an active member of the European Federation for Medicinal Chemistry (EFMC), whose mission is to advance the science of medicinal chemistry in Europe. EFMC promotes
Yves P. Auberson
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Heterocycles in Medicinal Chemistry
Molecules, 2019 Heteroatoms constitute a very common fragment of a number of active pharmaceutical ingredients as well as excipients; from the point of view of significance, it is all the same if these are isosterically/bioisosterically replaced carbons/carbon ...
Josef Jampilek
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Click Reactions in Medicinal Chemistry
Pharmaceuticals, 2023 Two decades after K [...]
Damien Bosc
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Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes–7
Molecules, 2020 Breakthroughs in Medicinal Chemistry: New Targets and Mechanisms, New Drugs, New Hopes is a series of editorials which is published on a biannual basis by the Editorial Board of the Medicinal Chemistry section of the journal Molecules [...]
Michael Gütschow +47 more
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