Results 141 to 150 of about 219,336 (313)
Phytochemical Constituents and Physicochemical Properties of Medicinal Plant (Moringa Oleifera) Around Bule Hora [PDF]
The investigation was carried out a qualitative test for the possible phytochemical components (Alkaloids, Phenolic compound, Quinone, Protein, Anthraquinones, Saponins, Coumarin, Flavonoids, Tannin Fixed oil and fats and Steroid-glycosides) and ...
Ibrahim Kassa Belay
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Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Shifting from Agriculture to Agribusiness: The Case of Aromatic Plants
This study has examined the agribusiness opportunities in medicinal and aromatic plants (MAPs), based on the field level information from the state of Uttarakhand. The financial feasibility of important aromatic plants has been studied. It has been found
Mittal, Rashi, Singh, S.P.
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Medicinal plant recipes from Kirklareli
In this study, have been reported different medicinal plant recipes in the Kirklareli region. 15 medicinal plant recipes belonging to 20 families (20 wild plant species, 7 cultivated plant species) which were used for different medicinal purposes by ...
KÜLTÜR, Şükran
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Background/Objectives: Modern sequencing technologies have transformed the identification of medicinal plant species and varieties, overcoming the limitations of traditional morphological and chemical approaches.
Mingcheng Wang +4 more
core +1 more source
Production of colchicine by using plant cell culture [PDF]
Plant cell and tissue culture is an established alternative to the harvest and extraction of whole plant material for the production of valuable secondary metabolites.
Aroud, Gamal
core

