Results 81 to 90 of about 9,984,497 (332)

Identification of Traditional Medicinal Plant Leaves Using an effective Deep Learning model and Self-Curated Dataset [PDF]

open access: yes
Medicinal plants have been a key component in producing traditional and modern medicines, especially in the field of Ayurveda, an ancient Indian medical system. Producing these medicines and collecting and extracting the right plant is a crucial step due to the visually similar nature of some plants.
arxiv   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

open access: yesMolecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu   +3 more
wiley   +1 more source

AI-driven Alternative Medicine: A Novel Approach to Drug Discovery and Repurposing [PDF]

open access: yesarXiv
AIAltMed is a cutting-edge platform designed for drug discovery and repurposing. It utilizes Tanimoto similarity to identify structurally similar non-medicinal compounds to known medicinal ones. This preprint introduces AIAltMed, discusses the concept of `AI-driven alternative medicine,' evaluates Tanimoto similarity's advantages and limitations, and ...
arxiv  

SMR: Medical Knowledge Graph Embedding for Safe Medicine Recommendation [PDF]

open access: yesarXiv, 2017
Most of the existing medicine recommendation systems that are mainly based on electronic medical records (EMRs) are significantly assisting doctors to make better clinical decisions benefiting both patients and caregivers. Even though the growth of EMRs is at a lighting fast speed in the era of big data, content limitations in EMRs restrain the existed
arxiv  

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

open access: yesMolecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam   +2 more
wiley   +1 more source

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