Results 121 to 130 of about 9,123,523 (313)

Pediatric Resuscitation: Evaluation of a Clinical Curriculum [PDF]

open access: yes, 2003
Objective: To assess the impact of a 6-hour pediatric resuscitation curriculum on the comfort levels of resident physicians’ evaluation and treatment of critically ill pediatric patients. Methods: An evaluation instrument assessed resident comfort levels,
Brancati , DO, David S.   +2 more
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Pentraxin-3 as a novel biomarker in predicting outcomes of nosocomial pneumonia: a prospective observational study

open access: yesMonaldi Archives for Chest Disease
Pneumonia, among all nosocomial infections, is known for its dismal prognosis, imposing substantial morbidity and mortality. While the diagnostic performance of various blood biomarkers has undergone scrutiny, their prognostic implications remain ...
Isha Garg   +9 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

A genetic algorithm to design Laue lenses with optimal performance for focusing hard X- and gamma-rays

open access: yes, 2014
In order to focus hard X- and gamma-rays it is possible to make use of a Laue lens as a concentrator. With this optical tool it would be possible to improve the detection of radiation for several applications, spanning from the observation of the most ...
Camattari, Riccardo, Guidi, Vincenzo
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Evidence-Based Medicine: A Resource for All

open access: yesCanadian Journal of Gastroenterology, 2002
LR Sutherland
doaj   +1 more source

Influence of Retirement on Adherence to Statins in the Insurance Medicine All-Sweden Total Population Data Base. [PDF]

open access: yesPLoS One, 2015
Halava H   +7 more
europepmc   +1 more source

Not All Inhaled Medicines Are Equal

open access: yesAnnals of the American Thoracic Society, 2022
Roy A. Pleasants, Stephen L. Tilley
openaire   +2 more sources

Medice, Cura Te Ipsum (Physician, Heal Thyself): A Documentary Film Exploring How the Passions of Medical Students Will Make Them Better and Healthier Physicians [PDF]

open access: yes, 2019
It is a well documented, yet largely ignored fact that physicians, residents and medical students are experiencing a pandemic of depression, burnout, dissatisfaction, and suicide.
Emhoff, Ryan
core   +1 more source

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