Results 31 to 40 of about 2,161,810 (255)

Applied physiology at the bedside: using invasive blood pressure as a true monitoring tool

Annals of Intensive Care
Invasive arterial blood pressure (BP) monitoring is a cornerstone of hemodynamic assessment in critically ill patients. This review explores how the individual components of BP—systolic arterial (SAP), diastolic arterial (DAP), mean arterial (MAP), and ...
Maxime Bertrand, Antoine Goury, Denis Chemla, Jean-Louis Teboul, Olfa Hamzaoui   +4 more
doaj   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source

Crosstalk between lung and extrapulmonary organs in sepsis-related acute lung injury/acute respiratory distress syndrome

Annals of Intensive Care
Sepsis-related acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is associated with considerable morbidity and mortality, yet the efficacy of current treatments is limited.
Bingyu Li, Weishan Lin, Ruomeng Hu, Songjie Bai, Yejiao Ruan, Yushi Fan, Shuya Qiao, Xuehuan Wen, Ruishan Liu, Heyu Chen, Wei Cui, Zhijian Cai, Gensheng Zhang   +12 more
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook, Veerain Gupta, Nicholas J. Clark, Vijay Rings, Lauren E. Corona, Douglass B. Clayton, Daniel J. Benedetti   +6 more
wiley   +1 more source

Improving Transitions of Care: Designing a Blockchain Application for Patient Identity Management

Blockchain in Healthcare Today, 2022
The annual ConV2X is a leading international health tech symposium driving real world evidence, strategy, research, operations and trends to create a blueprint for a new digital health era.
Mustafa Abdul-Moheeth. MD, Texas A&M Health Science Center College of Medicine, Daniel Toshio Harrell, PhD - Research Associate, Dell Medical School at the University of Texas at Austin, Anjum Khurshid, MD, PhD, Director, Data Integration, Co-Chief, Health Information and Data Analytic Sciences, Assistant Professor of Population Health, Affiliate Faculty, Center for Health Communication, Dell Medical School and The University of Texas   +2 more
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Preclinical Mouse Models in Sepsis: Don’t Throw the Baby Out with the Bathwater [Response to Letter]

Journal of Inflammation Research, 2023
Wendy E Walker,1,2 Luiz F Garcia,1 Vishwajeet Singh,3 Blake Mireles,2 Alok Kumar Dwivedi2–4 1Center of Emphasis in Infectious Diseases, Department of Molecular and Translational Medicine, Paul L.
Walker WE, Garcia LF, Singh V, Mireles B, Dwivedi AK   +4 more
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The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters, Ji Yun Tark, Tiffany M. Chambers, Tania A. Desrosiers, Michael E. Scheurer, Charles Shumate, Wendy N. Nembhard, Mahsa M. Yazdy, Eirini Nestoridi, Amanda E. Janitz, Jean Paul Tanner, Russell S. Kirby, Jason L. Salemi, Yao Yu, Chad D. Huff, Sharon E. Plon, Philip J. Lupo, Jeremy M. Schraw   +17 more
wiley   +1 more source

Alteration of Clinical Chemistry Parameters Among Visceral Leishmaniasis Patients in Western Tigrai, Ethiopia, 2018/2019: A Comparative Cross-Sectional Study

Infection and Drug Resistance, 2020
Brhane Tesfanchal,1 Gebremedhin Gebremichail,2 Getachew Belay,1 Gebreslassie Gebremariam,3 Gebreyohannes Teklehaimanot,4 Hagos Haileslasie,2 Getachew Kahsu,1 Aderajew Gebrewahd,5 Fitsum Mardu,6 Gebre Adhanom,5 Brhane Berhe,6 Hirut Teame,7 Aster Tsegaye,8
Tesfanchal B, Gebremichail G, Belay G, Gebremariam G, Teklehaimanot G, Haileslasie H, Kahsu G, Gebrewahd A, Mardu F, Adhanom G, Berhe B, Teame H, Tsegaye A, Wolde M   +13 more
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