Results 31 to 40 of about 103,668 (195)

Phyllanthi Fructus: A modal medicinal and food homologous item in quality evaluation

Chinese Herbal Medicines, 2023
Phyllanthi Fructus is a highly unique medicine and food homologous item, which exhibits distinctive flavor, notable nutritional value, and abundant pharmacological activity. It has enormous potential in the creation of health products and pharmaceuticals.
Li, Gefei, Jiang, Yurou, Zhang, Dingkun, Han, Li, Mo, Taigang, Fan, Sanhu, Huang, Haozhou, Lin, Junzhi   +7 more
openaire   +2 more sources

Extensive horizontal gene transfer in cheese-associated bacteria. [PDF]

, 2017
Acquisition of genes through horizontal gene transfer (HGT) allows microbes to rapidly gain new capabilities and adapt to new or changing environments.
Bonham, Kevin S, Dutton, Rachel J, Wolfe, Benjamin E   +2 more
core   +3 more sources

The role of biotransformation processes in mediating interactions between psychotropic drugs and natural products [PDF]

, 2020
Many patients are not aware that natural products such as fruit juices or plant infusions can cause significant interactions with several drugs, some of which can be dangerous, especially when the medical treatment is for neurological or psychiatric ...
Bacinschi, Nicolae, Chianu, Marin, Mihalachi-Anghel, Maria, Podgurschi, Lilia, Pogonea, Ina, Socea, Bogdan, Ștefănescu, Emil   +6 more
core   +2 more sources

Medicine and food homologous plant resources and their utilization in Guangxi: A review

Guangxi Zhiwu
Medicine and food homology refers to natural resources that possess both medicinal and edible values, representing a crucial component of traditional Chinese medicine theoretical system in China.
WU Chao, LIU Junkai, CHENG Simin, CHEN Yueyuan, SONG Jingru, ZHANG Xiujiao, ZHAO Shuaige, TANG Hui*
doaj   +1 more source

The establishment of a GPD1L knockout human embryonic stem cell line (WAe009-A-80) using the CRISPR/Cas9 system

Stem Cell Research
The GPD1L gene is located on 3p22.3. It encodes the glycerol phosphate dehydrogenase 1-like protein with homology to glycerol phosphate dehydrogenase (GPD1L), but the function of this enzyme is unclear.
Tao Dong, Yan Zhao, Hai-feng Jin, Hong-ming Pan, Li-ling Yue, Yan Lin, Lei Shen   +6 more
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Structural characterization and hypolipidemic activity of polysaccharides from finger citron

Journal of Functional Foods
In this study, the structural characterization and hypolipidemic activity in vivo of finger citron polysaccharide (FCP) were investigated. The FCP consisted of [→t)-Ara(f)-(1→], [→5)-Ara(f)-(1→], and [→4)-Gal(p)-UA-(1→] with the molecular weight of 46.35
Juan-Juan Ma, Xi Xie, Lu-Kai Ma, Qin Wang, Geng-Sheng Xiao, Hui-Fan Liu   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Multitarget mechanisms of the herb pair Achyranthes bidentata and Paeonia lactiflora Pall. in ameliorating hypertensive cardiomyopathy: combining network pharmacology and functional exploration

Frontiers in Pharmacology
The herb pair Achyranthes bidentata Blume and Paeonia lactiflora Pall. (AB-PL) has demonstrated significant efficacy in the treatment of hypertensive cardiomyopathy; however, its underlying mechanisms remain unclear.
Yanyan Zhang, Yanyan Zhang, Yingwanqi Wang, Jianing Liu, Yu Zhao, Yuhui He, Peimei Yan, Shan Ren, Ying Lyu, Weiwei Jia, Yuran Sun, Song Lin, Song Lin, Yan Lin, Yan Lin   +14 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source