Results 111 to 120 of about 3,738,036 (312)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Validity and reliability of the Japanese version of the CARE Measure in a general medicine outpatient setting [PDF]

, 2013
Muneyoshi Aomatsu, Hiroya Abe, K. Abe, Hironobu Yasui, Toshihiro Suzuki, Jun Sato, Nobutaro Ban, Stewart W Mercer   +7 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Supplementum 218: Annual Meeting of the Swiss Society of Gastroenterology (SGG), the Swiss Society of Visceral Surgery (SGVC) and the Swiss Association for the Study of the Liver (SASL) (Interlaken, Switzerland, September 22-23, 2016)

Swiss Medical Weekly, 2016
Swiss Society of General Internal Medicine, Swiss Society of Visceral Surgery, Swiss Association for the Study of the Liver   +2 more
doaj   +1 more source

Editorial: Highlights in General Cardiovascular Medicine: 2021

Frontiers in Cardiovascular Medicine, 2022
Lijun Wang, Lijun Wang, Longlu Pan, Pietro Enea Lazzerini, Junjie Xiao, Junjie Xiao   +5 more
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

The hospital educational environment and performance of residents in the General Medicine In-Training Examination: a multicenter study in Japan

, 2013
Taro Shimizu, Yusuke Tsugawa, Tanoue, Ryota Konishi, Yuji Nishizaki, Mitsumasa Kishimoto, Toshiaki Shiojiri, Yasuharu Tokuda   +7 more
openalex   +2 more sources

Facilitators and barriers to brokering between research and care by senior clinical-scientists in general practice and elderly care medicine [PDF]

, 2019
Marie-Louise Bartelink, Yvette Baggen, Diede Stevens, Martin Smalbrugge, Nynke Scherpbier, Roger Damoiseaux, Esther de Groot   +6 more
openalex   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Lateral thoracic artery aneurysm with lung abscess and empyema caused by Streptococcus intermedius

Journal of General and Family Medicine, 2021
Tatsuya Fujihara, Naoya Itoh, Shuhei Yamamoto, Hanako Kurai   +3 more
doaj   +1 more source