Results 131 to 140 of about 6,596,421 (354)

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Book Review: “Ultrasound for the Generalist: A Guide to Point-of- Care Imaging”

POCUS Journal, 2022
Daniel Restrepo
doaj   +1 more source

Pain medicine: general view to the problem

Медицина болю, 2017
The explosive growth of our knowledge of every aspect of pain in recent years has produced major advances in the classification and management of the varieties of pain.
M. G. Tsagareli
doaj  

Approach to the patient with metabolic syndrome in general medicine [PDF]

, 2017
Miloranka Petrov-Kiurski
openalex   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

<p>Experiences and Views of Medicine Information Among the General Public in Thailand</p>

, 2020
Kamonphat Wongtaweepkij, Janet Krska, Juraporn Pongwecharak, Narumol Jarernsiripornkul   +3 more
openalex   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

How Do We Establish the Utility and Evidence of General Medicine in Japan?

International Journal of General Medicine
Masaki Tago,1 Risa Hirata,1 Hiromizu Takahashi,2 Shun Yamashita,1,3 Masayuki Nogi,4,5 Kiyoshi Shikino,6 Yosuke Sasaki,7 Takashi Watari,8 Taro Shimizu9 1Department of General Medicine, Saga University Hospital, Saga, Japan; 2Department of General Medicine,
Tago M, Hirata R, Takahashi H, Yamashita S, Nogi M, Shikino K, Sasaki Y, Watari T, Shimizu T   +8 more
doaj  

General Internal Medicine

, 2020
Paul Bonisteel, İnci Arıkan, Ceylan Ayada, Mustafa Metin Donma, Orkide Donma, Deniz Gazel, Özlem Nazan Erdoğan, Suphi Vehid, Demet Dalca, Gülnaz Çiğ, Ahmet Oğul Araman, Anoka Njan, Mehmet Sarper Erdoğan, Erdem Ak, Cansu Koşar Şahin, Sezgi Çınar Pakyüz, Şeyma Kayalı, Aşkın Gülşen, Faika Başoğlu, Nuray Ulusoy Güzeldemirci   +19 more
openalex   +2 more sources