Results 171 to 180 of about 15,498,020 (343)

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Three layers in spinal canal

Journal of General and Family Medicine, 2023
Satoshi Inaba, Hisatoshi Okumura, Ayaka Kobayashi, Atsushi Kawashima   +3 more
doaj   +1 more source

Editorial: Insights in General Cardiovascular Medicine: 2021

Frontiers in Cardiovascular Medicine, 2022
Lijun Wang, Lijun Wang, Jianyun Liu, Yi Lu, Maurizio Acampa, Pier Leopoldo Capecchi, Pietro Enea Lazzerini, Junjie Xiao, Junjie Xiao   +8 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

How far on the road? The role of family medicine/general practice in 10 Central and Eastern European countries: A mixed-method study. [PDF]

Eur J Gen Pract
Oleszczyk M, Stepanovič A, Král N, Seifert B, Švab I, Krzysztoń J, Jagiełła N, Windak A.   +7 more
europepmc   +1 more source

Department of General Medicine [PDF]

, 2006
北 啓一朗, 山城 清二, 薄井 勲
core   +4 more sources

Editorial: Insights in general cardiovascular medicine: 2022

Frontiers in Cardiovascular Medicine, 2023
Maurizio Acampa, Riccardo Accioli, Viola Salvini, Junjie Xiao, Pietro Enea Lazzerini   +4 more
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

A Perspective on The Göktaş Definition of Family Medicine/General Practice: A Review of Singapore Quality. [PDF]

Pak J Med Sci
Goktas O.
europepmc   +1 more source