Results 181 to 190 of about 4,099,471 (214)

Comprehensive Characterization of 98 Chinese Cases of Genetic Creutzfeldt‐Jakob Disease With T188K Mutation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize the demographic, clinical, and laboratory features of the Chinese patients of genetic Creutzfeldt‐Jakob disease with T188K variant (T188K‐gCJD), the most common subtype of genetic prion diseases (gPrDs) in China. Methods In this nationwide retrospective study, data from 98 genetically confirmed T188K‐gCJD patients ...
Chun‐Jie Li, Dong‐Lin Liang, Li‐Ping Gao, Wei‐Wei Zhang, Wei Zhou, A. Ruhan, Bing Xu, Run‐Dong Cao, Kang Xiao, Cao Chen, Qi Shi, Xiao‐Ping Dong   +11 more
wiley   +1 more source

Rural-Urban and Appalachian Disparities in Geographic Access to Colonoscopy and Screening Prevalence Across the Contiguous US. [PDF]

Prev Chronic Dis
Namin S, Heidel RE, Whiteside M, Ferris J, Wall JS, McLoughlin JM.   +5 more
europepmc   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig, Nadav Amir, Maya Schiller, Roni Loebenstein, Johnatan Nissan, Marina Boxer, Shany Guly Gofrit, Gal Goshen, Sándor Beniczky, Nicola Maggio   +9 more
wiley   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Preferences for physician sex among adults attending Syrian public teaching hospitals: A multicenter cross-sectional study. [PDF]

PLoS One
Nasra AB, Abubakir M, Sabbagh L, Huseen Z, Nasra M, Almohammad Alibrahim MW, Zeitoun B, Kheder M, Morjan M.   +8 more
europepmc   +1 more source

<i>Microbacterium paraoxydans</i> Bloodstream Infection in a Patient with Long-Term Indwelling Central Venous Catheter: A Case Report and Literature Review. [PDF]

Microorganisms
Huang YK, Huang PH, Tseng CH, Liu CW, Huang WH, Huang HP, Liu PY, Yeh TK.   +7 more
europepmc   +1 more source

Sex differences in management and outcomes after out-of-hospital cardiac arrest with angiographically confirmed obstructive coronary artery disease. [PDF]

Resusc Plus
Svitekova K, Rob D, Mockova E, Kavalkova P, Pudil J, Dusik M, Macoun J, Svobodova E, Malik J, Valerianova A, Trhlikova S, Spicak J, Belohlavek J.   +12 more
europepmc   +1 more source